ATI RN
ATI Pharmacology Test Bank
1. A client has been prescribed Methotrexate to treat Rheumatoid Arthritis. Which of the following instructions should the nurse provide?
- A. Take this medication with food to prevent nausea.
- B. Avoid alcohol while taking this medication.
- C. Wear sunscreen when outdoors while taking this medication.
- D. Take this medication on an empty stomach.
Correct answer: B
Rationale: Methotrexate is hepatotoxic, and avoiding alcohol is crucial to prevent liver damage. However, Option A (Take this medication with food to prevent nausea) could also be correct, as Methotrexate commonly causes nausea, and taking it with food can help alleviate this side effect. However, the most important instruction is to avoid alcohol due to the risk of liver toxicity.
2. Which of the following types of insulin is classified as 'long-acting'?
- A. Lispro (Humalog)
- B. NPH (Humulin N)
- C. Regular insulin (Humulin R)
- D. Glargine (Lantus)
Correct answer: D
Rationale: The correct answer is Glargine (Lantus). Glargine is classified as a long-acting insulin due to its slow, steady release over an extended period, making it suitable for basal insulin requirements. It has a duration of action that can last up to 24 hours, helping to maintain stable blood sugar levels throughout the day. Lispro (Humalog) is a rapid-acting insulin, NPH (Humulin N) is an intermediate-acting insulin, and Regular insulin (Humulin R) is a short-acting insulin, so they are not classified as long-acting insulins.
3. A client has a new prescription for Metronidazole. Which of the following instructions should be included?
- A. Avoid drinking alcohol while taking this medication.
- B. Take the medication on an empty stomach.
- C. Increase your intake of green, leafy vegetables.
- D. Discontinue the medication if you experience a metallic taste.
Correct answer: A
Rationale: The correct instruction for a client prescribed Metronidazole is to avoid drinking alcohol while taking this medication. Metronidazole can cause a disulfiram-like reaction when combined with alcohol, resulting in severe nausea, vomiting, and other adverse effects. Therefore, it is crucial for clients to refrain from consuming alcohol during treatment to prevent these potential complications. Choice B is incorrect because Metronidazole can be taken with or without food. Choice C is irrelevant as there is no specific requirement to increase green, leafy vegetable intake with Metronidazole. Choice D is incorrect as a metallic taste is a known side effect of Metronidazole but does not necessarily indicate the need to discontinue the medication.
4. What is the action of Metformin?
- A. Decreasing intestinal glucose absorption
- B. Increasing sensitivity to insulin
- C. Decreasing hepatic glucose production
- D. All of the above
Correct answer: D
Rationale: Metformin exerts its effects by decreasing hepatic glucose production, increasing sensitivity to insulin, and decreasing intestinal glucose absorption. These actions help in lowering blood glucose levels and improving insulin sensitivity in individuals with diabetes.
5. A client has a new prescription for Warfarin. Which of the following herbal supplements should the client be instructed to avoid?
- A. St. John's wort
- B. Echinacea
- C. Garlic
- D. Ginseng
Correct answer: A
Rationale: St. John's wort should be avoided by clients taking Warfarin as it can reduce the medication's effectiveness by affecting its metabolism. Echinacea, garlic, and ginseng are also known to interact with Warfarin, either by increasing the risk of bleeding or altering its anticoagulant effects. However, St. John's wort is particularly significant due to its potent enzyme-inducing properties that can lead to subtherapeutic levels of Warfarin, potentially increasing the risk of blood clots.
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