ATI RN
WGU Pathophysiology Final Exam
1. When a healthcare professional notices that a patient has type O blood, they realize that anti-_____ antibodies are present in the patient's body.
- A. A only
- B. B only
- C. A and B
- D. O
Correct answer: C
Rationale: Individuals with type O blood have both anti-A and anti-B antibodies in their body. This is because type O blood lacks A or B antigens on the surface of red blood cells, causing the body to produce antibodies against both A and B antigens. Therefore, the correct answer is C. Choice A and B only antibodies are incorrect because type O individuals have both anti-A and anti-B antibodies. Choice D is incorrect as O represents the blood type itself, not the antibodies present in the blood.
2. How are antibodies produced?
- A. B cells
- B. T cells
- C. Helper cells
- D. Memory cells
Correct answer: A
Rationale: Antibodies are produced by B cells. B cells are specialized white blood cells that generate antibodies as part of the immune response. B cells differentiate into plasma cells that secrete antibodies. T cells play a role in cell-mediated immunity, not antibody production. Helper cells, or helper T cells, assist in activating B cells but do not directly produce antibodies. Memory cells store information about previous infections but do not actively produce antibodies.
3. A patient is taking raloxifene (Evista) for osteoporosis. What is the primary therapeutic effect of this medication?
- A. It stimulates the formation of new bone.
- B. It decreases bone resorption and increases bone density.
- C. It increases the excretion of calcium through the kidneys.
- D. It increases calcium absorption in the intestines.
Correct answer: B
Rationale: The correct answer is B. Raloxifene, a selective estrogen receptor modulator (SERM), primarily works by decreasing bone resorption and increasing bone density. This mechanism of action helps in the prevention and treatment of osteoporosis by maintaining or improving bone strength. Choice A is incorrect because raloxifene does not directly stimulate the formation of new bone but rather helps in preserving existing bone. Choice C is incorrect because raloxifene does not increase the excretion of calcium through the kidneys; instead, it acts on bone tissue. Choice D is incorrect as raloxifene does not directly increase calcium absorption in the intestines but rather focuses on bone health.
4. A patient is taking a statin for hyperlipidemia. What important instruction should the nurse provide to the patient?
- A. Take the medication at night to avoid muscle pain.
- B. Take the medication in the morning to ensure it works throughout the day.
- C. Avoid consuming alcohol while taking this medication.
- D. Take the medication with a high-fat meal to increase absorption.
Correct answer: A
Rationale: The correct answer is to instruct the patient to take the medication at night to avoid muscle pain. Statins are known to potentially cause muscle pain or weakness; taking the medication at night can help reduce the incidence of these side effects. Option B is incorrect because the timing of statin administration is not related to its effectiveness throughout the day. Option C is a general precaution when taking medications but not the most important instruction specific to statins. Option D is incorrect as taking the medication with a high-fat meal can actually decrease its absorption.
5. A patient's current medical condition is suggestive of impaired erythropoiesis. Which of the following laboratory studies would be most clinically relevant in diagnosing this health problem?
- A. White blood cell count with differential
- B. RBC, hemoglobin, and hematocrit
- C. INR and aPTT
- D. d-dimer and C-reactive protein
Correct answer: B
Rationale: In this scenario, where impaired erythropoiesis is suspected, the most clinically relevant laboratory studies would focus on red blood cell parameters. Therefore, assessing RBC count, hemoglobin levels, and hematocrit values would provide direct insights into erythropoiesis. Choices A, C, and D are not directly related to erythropoiesis assessment. White blood cell count with a differential is more indicative of immune response and infection. INR and aPTT are coagulation studies, while d-dimer and C-reactive protein levels are more associated with inflammation and thrombotic events.
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