Nursing Elites

1. What is the correct definition of drug absorption?

• A. Movement of a drug from the site of administration to various tissues of the body
• B. Describes the absorption, distribution, metabolism, and excretion of drugs
• C. These types of drugs can be taken over the counter
• D. This addresses how various drugs affect different forms of the body

Correct answer: A

Rationale: The correct definition of drug absorption is the movement of a drug from the site of administration into various tissues of the body. It is the process by which a drug is taken up and enters the systemic circulation. Choice B describes the pharmacokinetics of drugs, including absorption, distribution, metabolism, and excretion, but it is not a specific definition of drug absorption. Choice C is unrelated to drug absorption, as it refers to over-the-counter drugs. Choice D is too vague and does not specifically address the process of drug absorption.

2. A healthcare provider in a clinic is monitoring serum electrolytes for four older adult clients who take digoxin. Which of the following electrolyte values increases a client's risk for Digoxin toxicity?

• A. Calcium 9.2 mg/dL
• B. Calcium 10.3 mg/dL
• C. Potassium 3.4 mEq/L
• D. Potassium 4.8 mEq/L

Correct answer: C

Rationale: Potassium 3.4 mEq/L is below the expected reference range, which increases the risk for digoxin toxicity. Low potassium levels can lead to fatal dysrhythmias, particularly in older clients taking Digoxin. Hypokalemia potentiates the effects of Digoxin, making the heart more sensitive to its toxic effects. Monitoring and correcting electrolyte imbalances, especially low potassium levels, are crucial to prevent adverse effects of digoxin therapy. Calcium levels do not directly influence digoxin toxicity, so choices A and B are incorrect. High potassium levels, as in choice D, are less likely to increase the risk of digoxin toxicity compared to low potassium levels.

3. How is lithium typically administered?

• A. Intravenously
• B. Intramuscularly
• C. Orally
• D. Sublingually

Correct answer: C

Rationale: Lithium is typically administered orally to ensure proper absorption and distribution in the body. By taking lithium orally, it allows the medication to be absorbed through the gastrointestinal tract and distributed effectively. Intravenous and intramuscular routes are not commonly used for lithium administration as they can lead to rapid, unpredictable absorption and increase the risk of toxicity. Sublingual administration is also not the typical route for lithium, as it is usually taken orally for consistent and controlled absorption.

4. A client has a prescription for a Nitroglycerin transdermal patch. Which of the following instructions should be included by the healthcare provider?

• A. Apply the patch to a hairless area of the body.
• B. Remove the patch every 12 hours.
• C. Massage the patch after applying it.
• D. Place the patch over a hairless area of the body.

Correct answer: D

Rationale: The correct instruction for a Nitroglycerin transdermal patch is to place it over a hairless area of the body. This is essential to ensure proper adhesion and consistent absorption of the medication. Hair can impede the patch's ability to stick to the skin and deliver the medication effectively. Therefore, choices A, B, and C are incorrect. Applying the patch to the same site every day (Choice A) may lead to skin irritation, removing the patch every 12 hours (Choice B) is not typically recommended for Nitroglycerin patches, and massaging the patch after applying it (Choice C) could alter its integrity and affect drug delivery.

5. A client is admitted for a surgical procedure. Which of the following preexisting conditions can be a contraindication for the use of Ketamine as an intravenous anesthetic?

• A. Peptic ulcer disease
• B. Breast cancer
• C. Diabetes mellitus
• D. Schizophrenia

Correct answer: D

Rationale: Ketamine is known to produce psychological effects, such as hallucinations. Therefore, individuals with schizophrenia are at increased risk of experiencing exacerbation of their symptoms if given Ketamine, making it a contraindication for its use as an intravenous anesthetic. Peptic ulcer disease, breast cancer, and diabetes mellitus are not contraindications for Ketamine use as an intravenous anesthetic.

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