ATI RN
ATI Pathophysiology
1. Following a knee injury, a football player is taking ibuprofen, a nonsteroidal anti-inflammatory drug, for the control of pain. Which drug action is most likely to result in diminished sensation of pain for the player?
- A. Inhibition of cyclooxygenase (COX) enzymes
- B. Activation of opioid receptors
- C. Blocking of NMDA receptors
- D. Stimulation of serotonin receptors
Correct answer: A
Rationale: The correct answer is A: Inhibition of cyclooxygenase (COX) enzymes. Ibuprofen works by inhibiting these enzymes, which are involved in the production of prostaglandins that mediate pain and inflammation. This inhibition leads to decreased prostaglandin production, resulting in a decrease in pain and inflammation. Choices B, C, and D are incorrect because ibuprofen does not act on opioid receptors, NMDA receptors, or serotonin receptors to control pain. It primarily exerts its analgesic and anti-inflammatory effects through COX enzyme inhibition.
2. How can a nurse determine the efficacy of a child's mebendazole treatment for roundworm after 3 weeks?
- A. Liver function tests
- B. Stool for ova and parasites
- C. Colonoscopy or sigmoidoscopy
- D. Rectal swab for culture
Correct answer: B
Rationale: The correct answer is B: Stool for ova and parasites. To assess the efficacy of treatment for roundworm, the nurse would examine the stool for ova (eggs) and parasites. This test helps determine if the infection has been cleared. Choices A, C, and D are incorrect because liver function tests are not commonly used to monitor roundworm treatment efficacy, and colonoscopy/sigmoidoscopy as well as rectal swab for culture are not routine diagnostic tests for assessing the effectiveness of mebendazole treatment for roundworm.
3. After studying about viruses, which information indicates the student has a good understanding of viruses? Viruses:
- A. Contain no RNA or DNA
- B. Are capable of independent reproduction
- C. Replicate their genetic material inside host cells
- D. Are killed easily by antimicrobials
Correct answer: C
Rationale: The correct answer is C. Viruses replicate their genetic material inside host cells, which is a fundamental aspect of their life cycle. Choice A is incorrect because viruses contain either RNA or DNA. Choice B is incorrect as viruses cannot reproduce independently and rely on host cells for replication. Choice D is incorrect as viruses are not easily killed by antimicrobials due to their unique structure and mechanisms of infection.
4. Joseph, a 12-year-old child, complains to the school nurse about nausea and dizziness. While assessing the child, the nurse notices a black eye that looks like an injury. This is the third time in 1 month that the child has visited the nurse. Each time, the child provides vague explanations for various injuries. Which of the following is the school nurse’s priority intervention?
- A. Contact the child’s parents and ask about the child’s injuries.
- B. Encourage the child to be honest about the injuries.
- C. Question the teacher about the child's injuries.
- D. Report suspicion of abuse to the proper authorities.
Correct answer: D
Rationale: The school nurse's priority intervention in this situation is to report suspicion of abuse to the proper authorities. Given the pattern of unexplained injuries and vague explanations provided by the child, it raises significant concerns for possible abuse. Reporting to the appropriate authorities is crucial to ensure the child's safety and well-being. Contacting the child's parents (Choice A) may not be appropriate if abuse is suspected, as it could potentially put the child at further risk. Merely encouraging the child to be honest (Choice B) does not address the immediate safety concerns. Questioning the teacher (Choice C) is not the appropriate initial action when abuse is suspected; reporting to authorities should take precedence.
5. Which of the following statements describes an active cellular membrane exchange process?
- A. Sodium moving out of cells and potassium moving into cells
- B. The movement of water from an area of low solute concentration to an area of high solute concentration
- C. The movement of insulin using a protein to travel across the cell membrane
- D. Oxygen moving across the pulmonary capillaries to an area of high carbon dioxide
Correct answer: A
Rationale: The correct answer is A. In active transport, energy is expended to move substances against their concentration gradient. Sodium moving out of cells and potassium moving into cells is an example of active transport because it requires energy to pump these ions across the cell membrane against their concentration gradients. Choices B, C, and D describe passive processes where substances move along their concentration gradients without the input of energy.
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