ATI RN
ATI Pharmacology
1. A client has a new prescription for Beclomethasone. Which of the following instructions should the nurse include?
- A. Rinse your mouth after each use of this medication.
- B. Limit fluid intake while taking this medication.
- C. Increase your intake of vitamin B12 while taking this medication.
- D. You can take the medication as needed.
Correct answer: A
Rationale: The correct instruction for a client prescribed Beclomethasone is to rinse the mouth after each use to reduce the risk of oral fungal infection. Beclomethasone is a corticosteroid inhaler that can increase the risk of oral thrush, so rinsing the mouth helps minimize this side effect. Choice B is incorrect because there is no need to limit fluid intake while taking Beclomethasone. Choice C is incorrect as there is no specific need to increase vitamin B12 intake with this medication. Choice D is incorrect because Beclomethasone should be taken as prescribed, not as needed.
2. A healthcare professional in a provider's clinic is caring for a client who reports erectile dysfunction and requests a prescription for sildenafil. Which of the following medications currently prescribed for the client is a contraindication to taking sildenafil?
- A. Isosorbide
- B. Phenytoin
- C. Metronidazole
- D. Prednisone
Correct answer: A
Rationale: Sildenafil is contraindicated with nitrates like isosorbide due to the risk of severe hypotension. Isosorbide is a nitrate that can potentiate the hypotensive effects of sildenafil, leading to a dangerous drop in blood pressure. Therefore, it is essential to avoid concurrent use of isosorbide and sildenafil to prevent adverse effects. Phenytoin, metronidazole, and prednisone do not have significant interactions with sildenafil and are not contraindicated when used together.
3. What are the Therapeutic Effects of Lithium?
- A. Prevents or decreases the incidence of acute manic episodes
- B. Maintenance of blood glucose
- C. Control of hyperglycemia in diabetic patients
- D. Diminished seizure activity
Correct answer: A
Rationale: The therapeutic effect of lithium is that it prevents or decreases the incidence of acute manic episodes in patients with bipolar disorder. Lithium is commonly used as a mood stabilizer in the treatment of bipolar disorder due to its ability to reduce the frequency and severity of manic episodes. Choices B, C, and D are incorrect as lithium is not used for the maintenance of blood glucose, control of hyperglycemia in diabetic patients, or to diminish seizure activity. These effects are not associated with the use of lithium as a medication.
4. A client is taking oral Oxycodone and Ibuprofen in recommended doses. The nurse should identify that an interaction between these two medications will cause which of the following findings?
- A. A decrease in serum levels of ibuprofen, possibly leading to a need for increased doses of this medication.
- B. A decrease in serum levels of oxycodone, possibly leading to a need for increased doses of this medication.
- C. An increase in the expected therapeutic effect of both medications.
- D. An increase in expected adverse effects for both medications.
Correct answer: C
Rationale: When Oxycodone, a narcotic analgesic, and Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), are taken together, they work synergistically to enhance the pain-relieving effects of both medications. These drugs act through different mechanisms, leading to a combined analgesic effect that is more effective than when used alone. Therefore, the interaction between Oxycodone and Ibuprofen results in an increase in the expected therapeutic effect of both medications.
5. A healthcare professional is caring for a client who has a new prescription for Lisinopril. Which of the following laboratory values should the professional monitor?
- A. Serum potassium
- B. Serum sodium
- C. Serum calcium
- D. Serum magnesium
Correct answer: A
Rationale: Lisinopril is an ACE inhibitor that can cause hyperkalemia by reducing the excretion of potassium in the kidneys. Monitoring serum potassium levels is essential to prevent complications such as cardiac arrhythmias. Therefore, the healthcare professional should closely monitor the client's serum potassium levels when they are on Lisinopril. Choices B, C, and D are incorrect because Lisinopril primarily affects potassium levels due to its mechanism of action as an ACE inhibitor. Serum sodium, calcium, and magnesium levels are not typically affected by Lisinopril in the same way as potassium.
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