ATI RN
ATI Pharmacology
1. A client is prescribed Metformin. Which of the following laboratory values should be monitored to assess for potential adverse effects?
- A. Blood glucose
- B. Creatine kinase
- C. Hemoglobin A1c
- D. Serum creatinine
Correct answer: D
Rationale: The correct answer is D: Serum creatinine. Metformin can potentially cause lactic acidosis, particularly in patients with impaired renal function. Monitoring serum creatinine levels is crucial to assess kidney function and detect any adverse effects of Metformin on renal health. Choices A, B, and C are incorrect as blood glucose, creatine kinase, and hemoglobin A1c levels are not directly monitored to assess for potential adverse effects of Metformin. Blood glucose monitoring is typically done to assess the efficacy of antidiabetic medications like Metformin, while creatine kinase levels are indicative of muscle damage and hemoglobin A1c reflects long-term blood sugar control.
2. A client asks the nurse how Rituximab works, which the client is receiving to treat Non-Hodgkin's Leukemia. Which of the following should the nurse include?
- A. Blocks hormone receptors
- B. Increases immune response
- C. Binds with specific antigens on tumor cells
- D. Stops DNA replication during cell division
Correct answer: C
Rationale: Rituximab is a monoclonal antibody that binds with specific antigens on B-lymphocytes, leading to the destruction of cancer cells. In the context of Non-Hodgkin's Leukemia, Rituximab targets and destroys cancerous B-lymphocytes, which helps in treating the disease. Choices A, B, and D are incorrect. Rituximab does not block hormone receptors, increase immune response, or stop DNA replication during cell division. The primary mode of action of Rituximab is its binding with specific antigens on tumor cells, specifically B-lymphocytes, to elicit an immune response against cancerous cells.
3. A client has a new prescription for Omeprazole. Which of the following instructions should the nurse include?
- A. Take this medication before meals.
- B. Take this medication with food.
- C. Take this medication at bedtime.
- D. Take this medication with antacids.
Correct answer: A
Rationale: The correct answer is A: 'Take this medication before meals.' Omeprazole is a proton pump inhibitor that should be taken before meals to be most effective in reducing stomach acid production. Taking it before meals allows the medication to inhibit the proton pumps in the stomach when they are most active, leading to better control of acid secretion. Choice B is incorrect because taking Omeprazole with food may reduce its effectiveness as food can interfere with its absorption. Choice C is incorrect as Omeprazole is more effective when taken before meals. Choice D is incorrect as Omeprazole should not be taken with antacids as they can reduce its absorption.
4. A client has a new prescription for Digoxin to treat heart failure. Which of the following instructions should the nurse include in the teaching?
- A. Contact provider if heart rate is less than 60/min.
- B. Check pulse rate for 30 seconds and multiply the result by 2.
- C. Increase intake of sodium.
- D. Take with food if nausea occurs.
Correct answer: A
Rationale: The correct instruction for a client prescribed Digoxin for heart failure is to contact the provider if the heart rate is less than 60/min. Digoxin can affect heart rate, and a heart rate below 60/min may indicate toxicity, requiring prompt medical attention. Checking the pulse rate accurately and seeking medical advice are essential components of safe medication management. Choices B, C, and D are incorrect. Choice B is related to checking the pulse rate but does not address the critical action of contacting the provider if it is below 60/min. Increasing intake of sodium (Choice C) is inappropriate as high sodium levels can worsen heart failure. Taking Digoxin with food if nausea occurs (Choice D) does not address a critical aspect of Digoxin administration related to heart rate monitoring.
5. A client has a new prescription for Atenolol. Which of the following client statements indicates an understanding of the teaching?
- A. I should monitor my blood pressure regularly.
- B. I will take this medication at bedtime.
- C. I will take this medication with a high-fat meal.
- D. I should increase my intake of potassium-rich foods.
Correct answer: A
Rationale: The correct answer is A. Clients taking Atenolol, a beta-blocker, should monitor their blood pressure regularly to ensure the medication is effectively managing their condition. Monitoring blood pressure helps in assessing the drug's effectiveness and identifying any potential side effects that may influence blood pressure levels. Choices B, C, and D are incorrect because taking Atenolol at bedtime, with a high-fat meal, or increasing potassium-rich foods intake are not recommended actions associated with this medication and do not demonstrate an understanding of the teaching.
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