ATI RN
ATI Pharmacology Test Bank
1. A healthcare professional is preparing to administer vancomycin to a client. The professional should monitor for which of the following adverse effects?
- A. Nephrotoxicity
- B. Hepatotoxicity
- C. Red Man Syndrome
- D. Diarrhea
Correct answer: C
Rationale: Red Man Syndrome is a common adverse effect of vancomycin characterized by flushing and rash. It is not related to nephrotoxicity, hepatotoxicity, or diarrhea. Monitoring for this reaction allows for prompt intervention to prevent severe complications.
2. A client has a new prescription for Lovastatin. Which of the following instructions should be included?
- A. Take this medication on an empty stomach.
- B. Take this medication in the morning.
- C. Take this medication at bedtime.
- D. Increase your intake of potassium-rich foods.
Correct answer: C
Rationale: Lovastatin should be taken at bedtime because cholesterol production in the liver is highest at night, making the medication more effective in reducing cholesterol levels. By taking it at bedtime, the medication aligns with the body's natural rhythm of cholesterol synthesis, optimizing its therapeutic effects.
3. A client is starting therapy with cisplatin. The healthcare provider should instruct the client to report which of the following adverse effects?
- A. Tinnitus
- B. Nausea
- C. Constipation
- D. Weight gain
Correct answer: A
Rationale: The correct answer is tinnitus. Cisplatin can cause ototoxicity, which may manifest as tinnitus. Tinnitus should be reported promptly to the healthcare provider to prevent further hearing damage.
4. A healthcare provider is reviewing the health history of a client who is starting therapy with tamoxifen. The healthcare provider should recognize that tamoxifen is contraindicated in which of the following clients?
- A. A client with a history of deep-vein thrombosis
- B. A client with a history of migraine headaches
- C. A client with a history of hypertension
- D. A client with a history of anemia
Correct answer: A
Rationale: Tamoxifen is contraindicated in clients with a history of thromboembolic events, such as deep-vein thrombosis, due to the increased risk of blood clots. The estrogenic effects of tamoxifen can further increase the risk of thromboembolic events, making it unsafe for individuals with a history of deep-vein thrombosis. Choice B (migraine headaches), Choice C (hypertension), and Choice D (anemia) are not contraindications for tamoxifen therapy. Migraine headaches, hypertension, and anemia do not pose the same risk of adverse effects related to blood clot formation as deep-vein thrombosis does.
5. A nurse is teaching a client who has breast cancer about the adverse effects of chemotherapy. Which of the following statements should the nurse include?
- A. You should use a soft-bristled toothbrush to prevent bleeding.'
- B. You should take aspirin for minor aches and pains.'
- C. You should avoid contact with individuals who recently received live virus vaccines.'
- D. You should consume a diet low in protein to reduce the risk of renal damage.'
Correct answer: A
Rationale: The nurse should instruct the client to use a soft-bristled toothbrush to prevent bleeding, which can occur due to chemotherapy-induced thrombocytopenia.
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