ATI RN
ATI Pharmacology Proctored Exam 2023
1. A client in an acute care facility is receiving IV Nitroprusside for hypertensive crisis. The nurse should monitor the client for which of the following adverse reactions to this medication?
- A. Intestinal ileus
- B. Neutropenia
- C. Delirium
- D. Hyperthermia
Correct answer: C
Rationale: The correct answer is C: Delirium. When IV Nitroprusside is infused at high dosages, it can lead to thiocyanate toxicity, causing mental status changes such as delirium. It is crucial to monitor the thiocyanate levels to ensure they remain below 10 mg/dL during therapy to prevent adverse effects. Choices A, B, and D are incorrect because IV Nitroprusside is not commonly associated with intestinal ileus, neutropenia, or hyperthermia. Monitoring for delirium is crucial due to the risk of thiocyanate toxicity.
2. When teaching a client with a prescription for Loperamide for diarrhea, which instruction should the nurse include?
- A. Take the medication with a full glass of water.
- B. Avoid activities that require alertness.
- C. Expect abdominal pain and bloating.
- D. Take an additional dose after each loose stool.
Correct answer: B
Rationale: The correct instruction the nurse should include when teaching a client with a prescription for Loperamide is to 'Avoid activities that require alertness.' Loperamide can cause drowsiness, so clients should avoid such activities until they know how the medication affects them.
3. A client has a prescription for a Nitroglycerin transdermal patch. Which of the following instructions should be included by the healthcare provider?
- A. Apply the patch to a hairless area of the body.
- B. Remove the patch every 12 hours.
- C. Massage the patch after applying it.
- D. Place the patch over a hairless area of the body.
Correct answer: D
Rationale: The correct instruction for a Nitroglycerin transdermal patch is to place it over a hairless area of the body. This is essential to ensure proper adhesion and consistent absorption of the medication. Hair can impede the patch's ability to stick to the skin and deliver the medication effectively. Therefore, choices A, B, and C are incorrect. Applying the patch to the same site every day (Choice A) may lead to skin irritation, removing the patch every 12 hours (Choice B) is not typically recommended for Nitroglycerin patches, and massaging the patch after applying it (Choice C) could alter its integrity and affect drug delivery.
4. A client has a prescription for Clindamycin. Which of the following instructions should the nurse include?
- A. Take the medication with a full glass of water.
- B. Avoid taking the medication with food.
- C. Discontinue the medication if diarrhea occurs.
- D. Expect to have increased appetite while taking this medication.
Correct answer: A
Rationale: The correct instruction for a client taking Clindamycin is to take the medication with a full glass of water. Clindamycin can cause esophageal irritation, so taking it with a full glass of water helps minimize this risk. Avoiding taking the medication with food is not necessary. If diarrhea occurs, clients should not discontinue the medication without consulting their healthcare provider. Clindamycin is not known to cause increased appetite.
5. Which of the following is the antidote for Heparin toxicity?
- A. Protamine
- B. Methylene blue
- C. N-acetylcysteine
- D. Glucagon
Correct answer: A
Rationale: Protamine is the specific antidote for Heparin toxicity. Heparin is an anticoagulant medication, and if an overdose occurs or if there is excessive bleeding due to Heparin use, protamine, a positively charged molecule, can neutralize the anticoagulant effects of Heparin by forming a complex with it. This binding prevents Heparin from further inhibiting coagulation factors and helps in reversing its effects.
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