ATI RN
ATI Proctored Pharmacology Test
1. A client has a fungal infection and a new prescription for amphotericin B. Which of the following laboratory values should the nurse report to the provider before initiating the medication?
- A. Sodium 140 mEq/L
- B. Potassium 4.5 mEq/L
- C. BUN 55 mg/dL
- D. Glucose 120 mg/dL
Correct answer: C
Rationale: An elevated BUN level of 55 mg/dL should be reported before starting amphotericin B due to its nephrotoxic effects. Amphotericin B can cause kidney damage, and an elevated BUN indicates impaired kidney function, increasing the risk of further renal damage with this medication. Sodium, potassium, and glucose levels are not directly associated with the nephrotoxic effects of amphotericin B, making choices A, B, and D incorrect.
2. When preparing to administer IV Acyclovir for Herpes Zoster, what action should the nurse take?
- A. Infuse the medication over 1 hour.
- B. Monitor the client's blood pressure every 15 minutes during infusion.
- C. Administer a stool softener.
- D. Monitor the client's blood glucose level every 4 hours during infusion.
Correct answer: A
Rationale: The correct action for the nurse is to infuse IV Acyclovir over at least 1 hour to prevent nephrotoxicity. Rapid infusion can lead to adverse effects, so a slow infusion rate is crucial for patient safety. Monitoring blood pressure, administering a stool softener, or monitoring blood glucose levels are not directly related to the administration of IV Acyclovir for Herpes Zoster.
3. A client has a prescription for hydrochlorothiazide to treat hypertension. The nurse should monitor the client for which of the following adverse effects?
- A. Hypokalemia
- B. Hypertension
- C. Hyperglycemia
- D. Hypercalcemia
Correct answer: A
Rationale: Hydrochlorothiazide is a diuretic that can cause potassium loss, leading to hypokalemia. Monitoring potassium levels is crucial to prevent potential adverse effects such as cardiac arrhythmias and muscle weakness.
4. When a client has a new prescription for Warfarin, which of the following foods should they avoid based on the nurse's instructions?
- A. Broccoli
- B. Bananas
- C. Chicken
- D. Potatoes
Correct answer: A
Rationale: Clients prescribed Warfarin should avoid foods high in vitamin K, like broccoli, as they can counteract the medication's effectiveness. Warfarin works by inhibiting vitamin K-dependent clotting factors, so consuming high vitamin K foods can interfere with its anticoagulant effects. Bananas, chicken, and potatoes are not high in vitamin K and do not have a significant impact on Warfarin therapy.
5. A client has a new prescription for Furosemide. Which of the following adverse effects should the nurse monitor?
- A. Hyperkalemia
- B. Hyponatremia
- C. Hypernatremia
- D. Hypercalcemia
Correct answer: B
Rationale: Furosemide is a diuretic that commonly causes hyponatremia (low sodium levels) due to its effect on sodium and water excretion. The nurse must closely monitor the client for signs of hyponatremia, such as weakness, confusion, and muscle cramps, and promptly intervene to prevent complications. Choices A, C, and D are incorrect because Furosemide is not associated with hyperkalemia, hypernatremia, or hypercalcemia. Understanding the medication's mechanism of action helps prioritize monitoring for potential adverse effects.
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