ATI RN
ATI Pharmacology
1. A healthcare provider is reviewing the health care record of a client who is asking about conjugated equine estrogens. The provider should inform the client this medication is contraindicated in which of the following conditions?
- A. Atrophic vaginitis
- B. Dysfunctional uterine bleeding
- C. Osteoporosis
- D. Thrombophlebitis
Correct answer: D
Rationale: Conjugated equine estrogens are contraindicated in clients with a history of thrombophlebitis due to the increased risk of thrombotic events associated with estrogen use. Thrombophlebitis is characterized by inflammation of a vein with the formation of a clot, and estrogen can further exacerbate this condition, leading to serious complications. Choices A, B, and C are not contraindications for conjugated equine estrogens. Atrophic vaginitis and osteoporosis are conditions where estrogen therapy may actually be indicated. Dysfunctional uterine bleeding is another condition where estrogen therapy can be used to help regulate menstrual bleeding.
2. A client is prescribed Clopidogrel. Which of the following laboratory values should the nurse monitor to assess for potential adverse effects?
- A. White blood cell count
- B. Platelet count
- C. Hemoglobin
- D. Blood glucose
Correct answer: B
Rationale: Clopidogrel is an antiplatelet medication that works by inhibiting platelet aggregation. Therefore, the nurse should monitor the client's platelet count to assess for potential bleeding complications. Changes in platelet count can indicate the effectiveness of Clopidogrel therapy and help prevent adverse effects related to clotting or bleeding. Monitoring white blood cell count, hemoglobin, or blood glucose levels is not directly related to the action or side effects of Clopidogrel.
3. A client has a new prescription for Warfarin. Which of the following statements should the nurse include in the teaching?
- A. You will need to have your blood tested regularly while taking this medication.
- B. It is safe to take over-the-counter NSAIDs with this medication.
- C. You will need to avoid foods high in vitamin K while taking this medication.
- D. You will need to take this medication with food.
Correct answer: C
Rationale: Warfarin interacts with vitamin K, so clients should be instructed to avoid foods high in vitamin K. This is because vitamin K can interfere with the anticoagulant effects of Warfarin. It is important to maintain a consistent intake of vitamin K-containing foods to keep the medication working effectively. Therefore, the correct statement for the nurse to include in the teaching is to advise the client to avoid foods high in vitamin K while taking Warfarin. Choices A, B, and D are incorrect. Regular blood testing is necessary with Warfarin to monitor its effects and adjust the dosage if needed (Choice A). Taking over-the-counter NSAIDs with Warfarin is not safe due to an increased risk of bleeding (Choice B). Warfarin can be taken with or without food, so there is no specific requirement to take it with food (Choice D).
4. A client has a new prescription for Warfarin. Which of the following instructions should the nurse include?
- A. Avoid consuming foods high in vitamin K.
- B. Monitor your blood pressure regularly.
- C. Increase your intake of green, leafy vegetables.
- D. Take the medication with a high-fat meal.
Correct answer: A
Rationale: The correct answer is to advise the client to avoid consuming foods high in vitamin K. Warfarin's effectiveness can be affected by vitamin K intake. Clients should maintain a consistent intake of vitamin K and avoid sudden increases in foods high in vitamin K to ensure the medication works properly and consistently. Choices B, C, and D are incorrect. Monitoring blood pressure, increasing intake of green, leafy vegetables, or taking the medication with a high-fat meal are not specific instructions related to Warfarin therapy.
5. A client has a new prescription for Captopril. Which of the following instructions should the nurse include?
- A. Take the medication with food.
- B. Monitor your blood pressure weekly.
- C. Notify your provider if you develop a persistent cough.
- D. Avoid using salt substitutes to prevent hyperkalemia.
Correct answer: C
Rationale: The correct answer is to instruct the client to notify the provider if they develop a persistent cough. A persistent cough is a common adverse effect of Captopril and other ACE inhibitors. It is essential for the client to inform their healthcare provider promptly if this side effect occurs, as it may indicate a potentially serious issue that needs medical attention.
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