ATI RN
ATI Pharmacology
1. A client has a new prescription for a Nitroglycerin transdermal patch. Which of the following instructions should the nurse include?
- A. Apply the patch to a different site each day.
- B. Remove the patch at bedtime each day.
- C. Apply the patch over an area with little or no hair.
- D. Keep the patch on for 24 hours at a time.
Correct answer: B
Rationale: The correct instruction for a Nitroglycerin transdermal patch is to remove it each day, usually at bedtime, to prevent tolerance. Keeping the patch on for 24 hours at a time can lead to tolerance development. Applying the patch to a different site each day is not necessary, as long as the area is rotated to prevent skin irritation. Applying the patch over an area with little or no hair is not a critical instruction for the Nitroglycerin patch.
2. A client has a new prescription for Efavirenz, an NNRTI. Which of the following instructions should the nurse include?
- A. Take this medication at bedtime to prevent drowsiness.
- B. Take this medication with a glass of milk.
- C. Take this medication with a glass of juice.
- D. Take this medication at the same time every day.
Correct answer: A
Rationale: The correct instruction is to take Efavirenz at bedtime to prevent drowsiness and manage central nervous system side effects like dizziness and vivid dreams. While it is important to take the medication at the same time daily for consistent blood levels, the emphasis should be on bedtime to minimize the impact of these side effects. Choices B and C suggesting taking the medication with milk or juice are incorrect and not relevant to optimizing Efavirenz therapy.
3. In the management of nausea due to gastroparesis in a client with Diabetes, which of the following medications may be prescribed?
- A. Lubiprostone
- B. Metoclopramide
- C. Bisacodyl
- D. Loperamide
Correct answer: B
Rationale: Metoclopramide, as a dopamine antagonist, is commonly prescribed to manage nausea and improve gastric motility in clients with diabetic gastroparesis. By enhancing gastric emptying, it can help alleviate symptoms like bloating and nausea associated with gastroparesis. Choice A, Lubiprostone, is primarily used to treat chronic idiopathic constipation and irritable bowel syndrome with constipation, not nausea due to gastroparesis. Choice C, Bisacodyl, is a stimulant laxative used for the treatment of constipation and bowel preparation before procedures, not for nausea associated with gastroparesis. Choice D, Loperamide, is an antimotility agent used to manage diarrhea, not nausea or gastric motility issues seen in gastroparesis.
4. A client is receiving discharge instructions for a new prescription of Enoxaparin. Which of the following instructions should the provider include?
- A. Inject the medication into the muscle.
- B. Massage the injection site after administration.
- C. Rotate injection sites between the arms and thighs.
- D. Administer the medication in the abdomen.
Correct answer: D
Rationale: The correct answer is to administer the medication in the abdomen. Enoxaparin is administered as a subcutaneous injection in the abdomen to prevent bleeding complications. Injecting into the muscle or massaging the site can increase the risk of bleeding. Rotating sites between the arms and thighs is not recommended for Enoxaparin administration due to variations in absorption rates. Therefore, the provider should instruct the client to administer Enoxaparin in the abdomen for optimal effectiveness and safety.
5. A client is prescribed Atorvastatin. Which of the following laboratory values should be monitored to assess for potential adverse effects?
- A. Blood glucose
- B. Creatine kinase
- C. Hemoglobin
- D. Sodium
Correct answer: B
Rationale: Creatine kinase should be monitored in clients taking Atorvastatin as it can indicate muscle damage, a serious adverse effect of statins. Elevated creatine kinase levels may suggest myopathy or rhabdomyolysis, which are potential complications of statin therapy.
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