ATI RN
ATI Pharmacology Quizlet
1. A client is taking oral Oxycodone and Ibuprofen in recommended doses. The nurse should identify that an interaction between these two medications will cause which of the following findings?
- A. A decrease in serum levels of ibuprofen, possibly leading to a need for increased doses of this medication.
- B. A decrease in serum levels of oxycodone, possibly leading to a need for increased doses of this medication.
- C. An increase in the expected therapeutic effect of both medications.
- D. An increase in expected adverse effects for both medications.
Correct answer: C
Rationale: When Oxycodone, a narcotic analgesic, and Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), are taken together, they work synergistically to enhance the pain-relieving effects of both medications. These drugs act through different mechanisms, leading to a combined analgesic effect that is more effective than when used alone. Therefore, the interaction between Oxycodone and Ibuprofen results in an increase in the expected therapeutic effect of both medications.
2. A drug ending in the suffix (azole) is considered a ______.
- A. H
- B. ACE inhibitor
- C. Antifungal
- D. Beta agonist
Correct answer: C
Rationale: Drugs ending in the suffix -azole are commonly associated with antifungal medications. Examples include fluconazole, ketoconazole, and itraconazole. These medications are used to treat fungal infections by inhibiting the growth of fungi. Therefore, the correct answer is option C, 'Antifungal'. Options A, B, and D do not accurately describe drugs ending in -azole.
3. A client has a new prescription for Iron supplements. Which of the following instructions should be included?
- A. Take the medication with a glass of milk.
- B. Avoid taking the medication with orange juice.
- C. Increase fiber intake to prevent constipation.
- D. Expect stools to be bright red.
Correct answer: C
Rationale: The correct answer is C: 'Increase fiber intake to prevent constipation.' Iron supplements commonly cause constipation as a side effect. Increasing fiber intake can help alleviate this issue by promoting regular bowel movements and preventing constipation. Choice A is incorrect as iron absorption is hindered when taken with milk. Choice B is not directly related to iron supplements. Choice D is incorrect as iron supplements do not typically cause bright red stools.
4. A client has been taking Sertraline for the past 2 days. Which of the following assessment findings should alert the nurse to the possibility that the client is developing Serotonin syndrome?
- A. Bruising
- B. Fever
- C. Abdominal pain
- D. Rash
Correct answer: B
Rationale: Fever is a key symptom of serotonin syndrome, a potentially serious condition that can occur with the use of SSRIs like Sertraline. Serotonin syndrome is characterized by excessive levels of serotonin in the body, leading to symptoms such as fever, agitation, confusion, tremors, and sweating. If a client on Sertraline presents with fever, the nurse should consider the possibility of serotonin syndrome and take appropriate actions such as notifying the healthcare provider and monitoring the client closely. Bruising, abdominal pain, and rash are not typically associated with serotonin syndrome and are more likely to be indicative of other conditions or side effects.
5. A healthcare provider is providing discharge instructions to a client who is prescribed Enalapril. Which of the following adverse effects should the healthcare provider instruct the client to monitor?
- A. Dry cough
- B. Weight gain
- C. Diarrhea
- D. Nausea
Correct answer: A
Rationale: The correct answer is A: Dry cough. A persistent dry cough is a common adverse effect of Enalapril, an ACE inhibitor. Enalapril can cause a non-productive cough due to its effect on bradykinin levels. The client should be advised to report this symptom to their healthcare provider to consider alternative treatments. Choices B, C, and D are incorrect because weight gain, diarrhea, and nausea are not typically associated with Enalapril use.
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