ATI RN
ATI Pharmacology Quizlet
1. A client is taking oral Oxycodone and Ibuprofen in recommended doses. The nurse should identify that an interaction between these two medications will cause which of the following findings?
- A. A decrease in serum levels of ibuprofen, possibly leading to a need for increased doses of this medication.
- B. A decrease in serum levels of oxycodone, possibly leading to a need for increased doses of this medication.
- C. An increase in the expected therapeutic effect of both medications.
- D. An increase in expected adverse effects for both medications.
Correct answer: C
Rationale: When Oxycodone, a narcotic analgesic, and Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), are taken together, they work synergistically to enhance the pain-relieving effects of both medications. These drugs act through different mechanisms, leading to a combined analgesic effect that is more effective than when used alone. Therefore, the interaction between Oxycodone and Ibuprofen results in an increase in the expected therapeutic effect of both medications.
2. A healthcare provider is teaching a client who has a new prescription for Bisacodyl suppositories. Which of the following information should the provider include?
- A. Expect results within 15 to 60 minutes.
- B. Insert the suppository as directed by the healthcare provider.
- C. Keep the suppository at room temperature.
- D. Expect rectal burning.
Correct answer: D
Rationale: When educating a client about Bisacodyl suppositories, it is important to include information about the common side effects. Rectal burning is a frequent side effect that can occur after using Bisacodyl suppositories, so the client should be informed to expect this discomfort. The onset of action for Bisacodyl suppositories is typically within 15 to 60 minutes, so the client should expect results relatively quickly, not in 6 to 12 hours. It is essential to follow the healthcare provider's instructions on how to insert the suppository correctly. Keeping the suppository at room temperature is sufficient; refrigeration is not required. Therefore, option D is the correct choice as it addresses a common side effect and prepares the client for potential discomfort. Options A, B, and C are incorrect as they do not focus on a significant side effect, proper administration, or storage requirements.
3. A client in an acute care facility is receiving IV Nitroprusside for hypertensive crisis. The nurse should monitor the client for which of the following adverse reactions to this medication?
- A. Intestinal ileus
- B. Neutropenia
- C. Delirium
- D. Hyperthermia
Correct answer: C
Rationale: The correct answer is C: Delirium. When IV nitroprusside is administered at high dosages, it can lead to thiocyanate toxicity, resulting in mental status changes such as delirium. Monitoring thiocyanate levels during therapy is crucial to ensure they remain below 10 mg/dL to prevent this adverse reaction. Choices A, B, and D are incorrect because nitroprusside does not typically cause intestinal ileus, neutropenia, or hyperthermia as adverse reactions.
4. A client has Diabetes Mellitus, Pulmonary Tuberculosis, and a new prescription for Isoniazid. Which of the following supplements should the nurse expect to administer to prevent an adverse effect of INH?
- A. Ascorbic acid
- B. Pyridoxine
- C. Folic acid
- D. Cyanocobalamin
Correct answer: B
Rationale: Pyridoxine is administered with Isoniazid to prevent peripheral neuropathy, a common adverse effect of the drug. It is essential to provide this supplement to the client to minimize the risk of developing this adverse effect. Ascorbic acid (Vitamin C) is not typically given to prevent INH adverse effects. Folic acid and Cyanocobalamin are not commonly administered with INH for this purpose.
5. In which of the following cases is Lansoprazole not used?
- A. Gastritis
- B. Peptic Ulcers
- C. Zollinger-Ellison syndrome
- D. Thalamus hypertrophy
Correct answer: D
Rationale: Lansoprazole is a proton pump inhibitor mainly used to treat conditions related to the stomach, such as gastritis, peptic ulcers, and Zollinger-Ellison syndrome. Thalamus hypertrophy is not a condition that Lansoprazole is indicated for; it is used for gastrointestinal issues and not neurological conditions.
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