ATI RN
ATI Pharmacology Proctored Exam
1. A patient is receiving education about a new prescription for Omeprazole to manage heartburn. What information should the nurse include in the teaching?
- A. Take this medication at bedtime.
- B. This medication decreases the production of gastric acid.
- C. Take this medication 2 hours after eating.
- D. This medication can cause hyperkalemia.
Correct answer: B
Rationale: The correct information to include when teaching a patient about Omeprazole is that it decreases the production of gastric acid. Omeprazole works by inhibiting the proton pump in the stomach lining, thereby reducing acid secretion. This mechanism helps in managing heartburn symptoms effectively. Choice A is incorrect because Omeprazole is usually taken before a meal. Choice C is incorrect as Omeprazole is typically taken before meals, not after. Choice D is incorrect because hyperkalemia is not a common side effect of Omeprazole.
2. A client has a new prescription for rituximab. Which of the following findings should the nurse instruct the client to report?
- A. Dizziness
- B. Fever
- C. Urinary frequency
- D. Dry mouth
Correct answer: B
Rationale: The nurse should instruct the client to report fever. Fever can be an indication of an infection, a potential complication of rituximab therapy. Monitoring and reporting fever promptly can help in early intervention to prevent further complications. Dizziness, urinary frequency, and dry mouth are not typically associated with rituximab therapy and are less likely to be directly related to the medication. Therefore, they are not the priority findings to report in this scenario.
3. Which drug class has been found to decrease mortality if given within 8 hours of an MI due to a decrease in cardiac workload?
- A. Antiplatelets
- B. Beta-adrenergic blockers
- C. ACE inhibitors
- D. Calcium channel blockers
Correct answer: B
Rationale: Beta-adrenergic blockers have been shown to decrease mortality when administered within 8 hours of a myocardial infarction (MI). They do so by reducing cardiac workload, which helps improve outcomes post-MI. These drugs work by blocking the effects of adrenaline on the heart, leading to decreased heart rate, blood pressure, and myocardial oxygen demand, thereby protecting the heart muscle from further damage. This makes them a crucial part of the treatment regimen for acute coronary syndromes like MI.
4. A client is receiving IV Dopamine for the treatment of shock. Which of the following findings indicates that the medication is effective?
- A. Increased heart rate
- B. Decreased blood pressure
- C. Increased urine output
- D. Decreased respiratory rate
Correct answer: C
Rationale: Dopamine is a medication used in shock to increase cardiac output and improve renal perfusion. An increase in urine output indicates that the medication is effective as it shows improved renal perfusion and kidney function, which are essential for managing shock effectively. Choices A, B, and D are incorrect as an increased heart rate, decreased blood pressure, and decreased respiratory rate are not direct indicators of the effectiveness of IV Dopamine in treating shock.
5. Which drug undergoes extensive first-pass hepatic metabolism?
- A. Heparin
- B. Insulin
- C. Propranolol
- D. Nitroglycerin
Correct answer: C
Rationale: Propranolol undergoes extensive first-pass hepatic metabolism in the liver. When administered orally, propranolol is extensively metabolized by the liver before reaching systemic circulation, leading to reduced bioavailability. This process is known as first-pass hepatic metabolism, which significantly affects the drug's effectiveness and necessitates higher oral doses compared to other routes of administration. Heparin (Choice A) is not metabolized by the liver but excreted unchanged by the kidneys. Insulin (Choice B) is a peptide hormone that is not subject to significant first-pass metabolism. Nitroglycerin (Choice D) is primarily metabolized in the blood and tissues, bypassing significant first-pass metabolism in the liver.
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