ATI RN
ATI Pharmacology
1. When caring for a client receiving treatment with irinotecan, which of the following findings should the nurse monitor?
- A. Diarrhea
- B. Hypertension
- C. Ototoxicity
- D. Neutropenia
Correct answer: A
Rationale: The correct answer is diarrhea. Irinotecan commonly causes diarrhea as an adverse effect due to its impact on the gastrointestinal tract. Monitoring for diarrhea is essential to prevent dehydration and manage this side effect effectively. Choices B, C, and D are incorrect as hypertension, ototoxicity, and neutropenia are not commonly associated with irinotecan therapy.
2. A client has a new prescription for metronidazole. The client should avoid which of the following?
- A. Dairy products
- B. Alcohol
- C. Leafy green vegetables
- D. Grapefruit juice
Correct answer: B
Rationale: The correct answer is B: Alcohol. Clients should avoid alcohol while taking metronidazole to prevent a disulfiram-like reaction, which can cause symptoms such as nausea, vomiting, headache, and flushing. Alcohol can interact with metronidazole and lead to adverse effects. Choices A, C, and D are not typically contraindicated with metronidazole. Dairy products, leafy green vegetables, and grapefruit juice do not have significant interactions with metronidazole, unlike alcohol.
3. A client is being discharged with a new prescription for furosemide 40 mg PO daily. Which of the following instructions should be included?
- A. Avoid foods rich in potassium.
- B. Take the medication with food.
- C. Weigh yourself daily.
- D. Stand up slowly to minimize orthostatic hypotension.
Correct answer: D
Rationale: The correct answer is D: 'Stand up slowly to minimize orthostatic hypotension.' Clients prescribed furosemide are at risk for orthostatic hypotension, a sudden drop in blood pressure when changing positions. Advising the client to stand up slowly can help prevent this complication. Instructing the client to avoid rapid position changes decreases the likelihood of dizziness or fainting episodes. Choices A, B, and C are incorrect because furosemide does not require avoiding potassium-rich foods, taking the medication with food, or daily weighing as specific instructions.
4. What is the classification of furosemide?
- A. Loop diuretic
- B. Anticoagulant
- C. Iron supplement
- D. Anticonvulsant
Correct answer: A
Rationale: Furosemide is classified as a loop diuretic, not an anticoagulant, iron supplement, or anticonvulsant. Loop diuretics, like furosemide, act in the loop of Henle in the kidney to inhibit sodium and chloride reabsorption, leading to increased urine output. This mechanism makes them effective in treating conditions such as edema and hypertension. Therefore, the correct classification for furosemide is a loop diuretic (Choice A).
5. A client presents in the Emergency Department with a suspected MI. Which medication should NOT be given as soon as possible?
- A. Clopidogrel (Plavix)
- B. Morphine
- C. Aspirin (ASA)
- D. Metoprolol (Lopressor)
Correct answer: A
Rationale: In the setting of a suspected myocardial infarction (MI), the priority medications to administer as soon as possible include aspirin (ASA) and possibly morphine to manage pain and anxiety. Clopidogrel (Plavix) is not typically administered immediately in the emergency setting for MI management. Metoprolol (Lopressor) is indicated after aspirin administration and stabilization of the patient. Therefore, in this scenario, clopidogrel should NOT be given as a first-line medication for a suspected MI.
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