a nurse is caring for a client who is receiving treatment with irinotecan which of the following findings should the nurse monitor

ATI RN

ATI Pharmacology

1. When caring for a client receiving treatment with irinotecan, which of the following findings should the nurse monitor?

A. Diarrhea
B. Hypertension
C. Ototoxicity
D. Neutropenia

Correct answer: A

Rationale: The correct answer is diarrhea. Irinotecan commonly causes diarrhea as an adverse effect due to its impact on the gastrointestinal tract. Monitoring for diarrhea is essential to prevent dehydration and manage this side effect effectively. Choices B, C, and D are incorrect as hypertension, ototoxicity, and neutropenia are not commonly associated with irinotecan therapy.

2. Which of the following conditions is not treated with Methotrexate?

A. Sarcomas
B. Leukemias
C. Ectopic pregnancy
D. Rheumatic fever

Correct answer: D

Rationale: The correct answer is D. Methotrexate is not typically used to treat rheumatic fever, which is more commonly managed with antibiotics to eradicate the underlying infection. Methotrexate is commonly used in the treatment of conditions like sarcomas, leukemias, and ectopic pregnancies due to its anti-inflammatory and anti-cancer properties.

3. A client is prescribed Propylthiouracil (PTU) for the treatment of Graves' disease. Which adverse effect should the client be instructed to report?

A. Sore throat.
B. Drowsiness.
C. Urinary retention.
D. Heat intolerance.

Correct answer: A

Rationale: The correct answer is A: Sore throat. A sore throat and fever can indicate agranulocytosis, a serious adverse effect of PTU that can lead to a decreased white blood cell count. This condition requires immediate medical attention to prevent complications. Choice B, drowsiness, is not typically associated with PTU and is not a common adverse effect that needs to be reported. Choice C, urinary retention, is not a typical adverse effect of PTU; therefore, it is not the correct answer. Choice D, heat intolerance, is a symptom commonly seen in hyperthyroidism, which PTU is used to treat, so it is not an adverse effect that needs to be specifically reported.

4. What classification of drug is Penicillin?

A. Antiarrhythmic
B. Anticonvulsant
C. Antibacterial
D. Mood stabilizer

Correct answer: C

Rationale: Penicillin is classified as an antibacterial drug, specifically used to treat bacterial infections. It works by inhibiting the growth of bacteria, making it an effective treatment for various bacterial infections. Choices A, B, and D are incorrect as Penicillin does not belong to these drug classifications. Penicillin does not have any direct effect on heart rhythm (antiarrhythmic), does not treat seizures (anticonvulsant), and is not used to stabilize mood (mood stabilizer).

5. A client has a new prescription for metronidazole. The client should avoid which of the following?

A. Dairy products
B. Alcohol
C. Leafy green vegetables
D. Grapefruit juice

Correct answer: B

Rationale: The correct answer is B: Alcohol. Clients should avoid alcohol while taking metronidazole to prevent a disulfiram-like reaction, which can cause symptoms such as nausea, vomiting, headache, and flushing. Alcohol can interact with metronidazole and lead to adverse effects. Choices A, C, and D are not typically contraindicated with metronidazole. Dairy products, leafy green vegetables, and grapefruit juice do not have significant interactions with metronidazole, unlike alcohol.