ATI RN
ATI Pharmacology
1. A client is starting therapy with bicalutamide. Which of the following adverse effects should the nurse instruct the client to monitor?
- A. Muscle pain
- B. Flushing
- C. Gynecomastia
- D. Hyperglycemia
Correct answer: C
Rationale: The correct answer is gynecomastia (Choice C). Bicalutamide is associated with gynecomastia due to its antiandrogenic properties. Gynecomastia, the development of breast tissue in males, is an important adverse effect to monitor when taking bicalutamide. Choices A, B, and D are incorrect. Muscle pain and flushing are not commonly associated with bicalutamide use. Hyperglycemia is not a typical adverse effect of bicalutamide therapy.
2. A client with Angina Pectoris asks the nurse about the next step if one tablet does not relieve Anginal pain after waiting 5 minutes. Which of the following responses should the nurse make?
- A. Take two more sublingual tablets simultaneously.
- B. Call emergency services.
- C. Take a sustained-release nitroglycerin capsule.
- D. Wait another 5 minutes before taking a second sublingual tablet.
Correct answer: B
Rationale: In a situation where Anginal pain persists after taking one sublingual tablet and waiting 5 minutes, it is crucial to call emergency services (911) immediately. This could indicate a myocardial infarction (heart attack) rather than a typical Anginal attack. The client should not take two more sublingual tablets simultaneously without seeking immediate medical help as this could delay appropriate intervention if the pain is due to a heart attack. Taking a sustained-release nitroglycerin capsule is not recommended for immediate relief of acute Anginal pain as it works too slowly. Waiting another 5 minutes before taking a second sublingual tablet is not appropriate if the pain persists, as prompt action is essential in suspected heart-related issues.
3. A client has a new prescription for Iron supplements. Which of the following instructions should be included?
- A. Take the medication with a glass of milk.
- B. Avoid taking the medication with orange juice.
- C. Increase fiber intake to prevent constipation.
- D. Expect stools to be bright red.
Correct answer: C
Rationale: The correct answer is C: 'Increase fiber intake to prevent constipation.' Iron supplements commonly cause constipation as a side effect. Increasing fiber intake can help alleviate this issue by promoting regular bowel movements and preventing constipation. Choice A is incorrect as iron absorption is hindered when taken with milk. Choice B is not directly related to iron supplements. Choice D is incorrect as iron supplements do not typically cause bright red stools.
4. A client with chronic kidney disease has a new prescription for epoetin alfa. The nurse should instruct the client to increase dietary intake of which of the following substances?
- A. Iron
- B. Protein
- C. Potassium
- D. Sodium
Correct answer: A
Rationale: Patients with chronic kidney disease are often prescribed epoetin alfa to treat anemia. Epoetin alfa stimulates red blood cell production, increasing the body's demand for iron to support this process. Therefore, clients taking epoetin alfa should be advised to increase their dietary intake of iron-rich foods to meet the increased demand and prevent iron deficiency anemia. Choices B, C, and D are incorrect because while protein is essential for overall health, potassium and sodium intake may need to be restricted in clients with chronic kidney disease to manage electrolyte balance and blood pressure.
5. Which of the following is the antidote for benzodiazepine toxicity?
- A. Flumazenil
- B. Methylene blue
- C. Deferoxamine
- D. Alkalinize urine
Correct answer: A
Rationale: Flumazenil is the specific antidote for benzodiazepine toxicity. It acts as a competitive antagonist at the benzodiazepine binding site on the GABA receptor, reversing the sedative effects of benzodiazepines. Administration of flumazenil is indicated in cases of benzodiazepine overdose or toxicity to rapidly reverse the central nervous system depression caused by these drugs. It is important to note that flumazenil should be used cautiously in patients with a history of seizures or those who are physically dependent on benzodiazepines, as it can precipitate withdrawal symptoms or seizures.
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