ATI RN
ATI Pharmacology
1. A client is starting therapy with bicalutamide. Which of the following adverse effects should the nurse instruct the client to monitor?
- A. Muscle pain
- B. Flushing
- C. Gynecomastia
- D. Hyperglycemia
Correct answer: C
Rationale: The correct answer is gynecomastia (Choice C). Bicalutamide is associated with gynecomastia due to its antiandrogenic properties. Gynecomastia, the development of breast tissue in males, is an important adverse effect to monitor when taking bicalutamide. Choices A, B, and D are incorrect. Muscle pain and flushing are not commonly associated with bicalutamide use. Hyperglycemia is not a typical adverse effect of bicalutamide therapy.
2. A healthcare professional is obtaining a medication history from a client who is to receive Imipenem-cilastatin IV to treat an infection. Which of the following medications the client also receives puts them at risk for a medication interaction?
- A. Regular insulin
- B. Furosemide
- C. Valproic acid
- D. Ferrous sulfate
Correct answer: C
Rationale: The correct answer is C, Valproic acid. Imipenem-cilastatin decreases the blood levels of valproic acid, an antiseizure medication, which can lead to increased seizure activity. Monitoring and adjusting the dosage of valproic acid may be necessary when co-administered with Imipenem-cilastatin to prevent adverse effects. Choices A, B, and D do not typically interact significantly with Imipenem-cilastatin and are not associated with a high risk of adverse interactions in this scenario.
3. How can the nurse best explain the difference between angina and a myocardial infarction to a client presenting with severe chest pain?
- A. “Angina usually resolves with rest, and is rarely fatal, while a myocardial infarction necessitates immediate treatment and can be life-threatening.”
- B. “There is a clear distinction between the two. You will receive treatment based on the diagnosis of a myocardial infarction.”
- C. “Both conditions result from a clot obstructing the coronary arteries. Angina occurs with the blockage of a small vessel, whereas a myocardial infarction occurs with a blockage of a large vessel.”
- D. “Angina may not cause as intense chest pain, whereas a myocardial infarction always presents with severe chest pain.”
Correct answer: A
Rationale: When educating a client about the differences between angina and a myocardial infarction, it is crucial to emphasize key distinguishing factors. Angina typically improves with rest and is not usually life-threatening, whereas a myocardial infarction requires urgent intervention as it can be life-threatening. This explanation helps the client understand the urgency and severity associated with a myocardial infarction compared to angina.
4. A client has a new prescription for Clonidine. Which of the following instructions should the nurse include?
- A. Expect to feel drowsy.
- B. Increase your intake of high-potassium foods.
- C. Take the medication with grapefruit juice.
- D. Avoid foods high in fat.
Correct answer: A
Rationale: The correct answer is to expect to feel drowsy. Clonidine is known to cause drowsiness, especially at the beginning of treatment. It is important for clients to be cautious with activities that require alertness until they understand how the medication affects them. Choice B is incorrect as there is no specific need to increase high-potassium foods with Clonidine. Choice C is incorrect as grapefruit juice can interact with many medications but is not a typical instruction for Clonidine. Choice D is incorrect as there is no specific indication to avoid foods high in fat with Clonidine.
5. A client is prescribed Amlodipine. Which of the following adverse effects should the nurse monitor?
- A. Tachycardia
- B. Peripheral edema
- C. Hyperglycemia
- D. Hypertension
Correct answer: B
Rationale: Corrected Rationale: Amlodipine is a calcium channel blocker known to cause peripheral edema as an adverse effect. The nurse should monitor the client for swelling, particularly in the lower extremities, as it can indicate the development of this side effect. Choice A, Tachycardia, is not a common adverse effect of Amlodipine. Choice C, Hyperglycemia, is not typically associated with Amlodipine use. Choice D, Hypertension, is the condition Amlodipine is prescribed to treat, not an adverse effect of the medication.
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