ATI RN
ATI Proctored Pharmacology 2023
1. A client with osteoporosis has a new prescription for alendronate. Which of the following instructions should the nurse provide?
- A. Take the medication with a meal.
- B. Remain upright for at least 30 minutes after taking the medication.
- C. Take the medication with a glass of juice.
- D. Take the medication with milk or food.
Correct answer: B
Rationale: The correct instruction for a client taking alendronate is to remain upright for at least 30 minutes after administration. This is essential to prevent esophageal irritation and ensure the medication reaches the stomach properly. Remaining upright reduces the risk of side effects such as esophagitis. Choices A, C, and D are incorrect as alendronate should not be taken with a meal, juice, milk, or food to optimize its absorption and effectiveness.
2. A client is taking Amiodarone to treat Atrial Fibrillation. Which of the following findings is a manifestation of Amiodarone toxicity?
- A. Light yellow urine
- B. Report of tinnitus
- C. Productive cough
- D. Blue-gray skin discoloration
Correct answer: D
Rationale: Blue-gray skin discoloration is a common sign of Amiodarone toxicity, known as blue-gray discoloration, which can affect areas like the face, neck, or hands. It is important to monitor for this side effect, as it can be a visible indicator of potential toxicity. Choices A, B, and C are incorrect. Light yellow urine is not typically associated with Amiodarone toxicity. Tinnitus is not a common manifestation of Amiodarone toxicity. A productive cough is not a recognized symptom of Amiodarone toxicity.
3. Which adverse reaction poses the greatest life-threatening risk when taking Omeprazole?
- A. Chest pain
- B. Constipation
- C. Clostridium difficile-associated diarrhea
- D. Acute interstitial nephritis
Correct answer: C
Rationale: The most life-threatening adverse reaction associated with Omeprazole is Clostridium difficile-associated diarrhea. This condition can be severe and life-threatening due to the potential for dehydration, electrolyte imbalances, and complications such as toxic megacolon. Chest pain, constipation, and acute interstitial nephritis are potential side effects of Omeprazole but are not considered as life-threatening as Clostridium difficile-associated diarrhea. Monitoring for signs of this adverse reaction is crucial, and immediate medical attention should be sought if symptoms develop.
4. Which of the following drugs is associated with the reaction of Cinchonism?
- A. Valproic acid
- B. Quinidine
- C. Isoniazid
- D. Ethosuximide
Correct answer: B
Rationale: Cinchonism is associated with Quinidine, not Valproic acid, Isoniazid, or Ethosuximide. Cinchonism is characterized by symptoms such as tinnitus, dizziness, and headaches. Quinidine, being an antiarrhythmic agent, can lead to this condition as a side effect.
5. A client has a new prescription for Prednisone. Which of the following instructions should be included?
- A. Increase your intake of vitamin D.
- B. Take this medication on an empty stomach.
- C. Avoid drinking grapefruit juice.
- D. Take this medication every other day.
Correct answer: A
Rationale: When a client is prescribed Prednisone, it is important to increase the intake of vitamin D to help mitigate the risk of bone loss associated with the medication. Vitamin D aids in calcium absorption, supporting bone health in individuals taking Prednisone.
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