which of the following is not an effect of the drug clozapine
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Nursing Elites

ATI RN

ATI Pharmacology Proctored

1. Which of the following is not a known effect of the drug Clozapine?

Correct answer: D

Rationale: Clozapine is associated with side effects like agranulocytosis (a serious blood condition), sedation (not hyperactivity), and is used as an antipsychotic to treat schizophrenia. Hyperactivity is not a typical effect of Clozapine, making it the correct answer in this context.

2. The healthcare professional is preparing to administer atenolol (Tenormin) to a client with angina. Which vital sign would cause the healthcare professional to question administering this drug?

Correct answer: B

Rationale: Atenolol is a beta-blocker medication that can lower heart rate. A pulse of 52 beats per minute is relatively low and administering atenolol could further decrease the heart rate, potentially leading to bradycardia. Monitoring the pulse rate and holding the medication if the pulse is below the prescribed parameters is crucial to prevent adverse effects such as bradycardia and hypotension.

3. A client receiving chemotherapy with Methotrexate asks why Leucovorin is being given. Which of the following responses should the nurse use?

Correct answer: D

Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment. Choices A, B, and C are incorrect because Leucovorin does not reduce the risk of a transfusion reaction from Methotrexate, increase platelet production, prevent bleeding, or potentiate the cytotoxic effects of Methotrexate. Instead, Leucovorin works by rescuing healthy cells from the toxic effects of Methotrexate.

4. When teaching a client with a prescription for Vancomycin, which instruction should the nurse include?

Correct answer: D

Rationale: The correct answer is D. Vancomycin is known to cause ototoxicity, which can result in hearing loss. Therefore, it is important for clients to monitor for any changes in their hearing while taking this medication and promptly report any issues to their healthcare provider for further evaluation and management. Choices A, B, and C are incorrect because red man syndrome is associated with rapid infusion of Vancomycin, not a common side effect during treatment; taking the medication with a full glass of water is a general instruction for many medications but not specific to Vancomycin; and increasing potassium-rich foods is not directly related to Vancomycin therapy.

5. What is the antidote for Warfarin?

Correct answer: B

Rationale: The correct antidote for Warfarin is Vitamin K. Warfarin works by inhibiting vitamin K-dependent clotting factors. Administering Vitamin K helps reverse its effects by replenishing these factors. Choices A, C, and D are incorrect. Naloxone is used to reverse opioid overdose, Glucagon is used to treat severe low blood sugar, and Vitamin B is not the antidote for Warfarin.

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