a nurse is preparing to administer a transfusion of 300 ml of pooled platelets for a client who has severe thrombocytopeni the nurse should plan to ad

ATI RN

ATI Pharmacology Proctored Exam

1. A healthcare professional is preparing to administer a transfusion of 300 mL of pooled platelets for a client who has severe Thrombocytopenia. How long should the healthcare professional plan to administer the transfusion over?

A. Within 30 min/unit
B. Within 60 min/unit
C. Within 2 hr/unit
D. Within 4 hr/unit

Correct answer: A

Rationale: Platelets are fragile components that must be administered quickly to maintain their effectiveness and minimize the risk of clumping. The recommended administration time for platelets is within 15 to 30 minutes per unit. This rapid administration helps ensure the platelets remain viable and functional for the client receiving the transfusion. Therefore, the correct answer is to administer the transfusion within 30 minutes per unit. Choices B, C, and D are incorrect as they exceed the recommended administration time for platelets, which could compromise their efficacy and pose risks to the client.

2. Which of the following is the antidote for benzodiazepine toxicity?

A. Flumazenil
B. Methylene blue
C. Deferoxamine
D. Alkalinize urine

Correct answer: A

Rationale: Flumazenil is the specific antidote for benzodiazepine toxicity. It acts as a competitive antagonist at the benzodiazepine binding site on the GABA receptor, reversing the sedative effects of benzodiazepines. Administration of flumazenil is indicated in cases of benzodiazepine overdose or toxicity to rapidly reverse the central nervous system depression caused by these drugs. It is important to note that flumazenil should be used cautiously in patients with a history of seizures or those who are physically dependent on benzodiazepines, as it can precipitate withdrawal symptoms or seizures.

3. A client has a new prescription for Metoprolol. Which of the following instructions should the nurse include?

A. Take this medication with food.
B. Monitor for signs of hyperglycemia.
C. Avoid sudden discontinuation of the medication.
D. Increase your intake of potassium-rich foods.

Correct answer: C

Rationale: The correct answer is to instruct the client to avoid sudden discontinuation of Metoprolol. Metoprolol is a beta-blocker that should be tapered off gradually to prevent rebound hypertension and other cardiac issues. Abruptly stopping Metoprolol can lead to serious complications, so it is essential for the client to follow the healthcare provider's guidance on discontinuation. Choice A is incorrect because Metoprolol can be taken with or without food. Choice B is incorrect as Metoprolol is not typically associated with causing hyperglycemia. Choice D is also incorrect as there is no need to increase potassium-rich foods specifically due to taking Metoprolol.

4. What is one of the therapeutic uses of Valproate?

A. Suppression of seizure activity
B. Replacement of hypothyroidism to restore normal hormone balance
C. Maintenance of blood glucose
D. Lowering of blood pressure

Correct answer: A

Rationale: Valproate, also known as Valproic acid, is commonly used in medicine for the suppression of seizure activity. It is an anticonvulsant medication that helps manage and prevent seizures in various conditions such as epilepsy. While it is not used for replacing hypothyroidism, maintaining blood glucose levels, or lowering blood pressure, its primary therapeutic use is in managing seizures.

5. What is the pharmacological class of Lithium?

A. Antidiabetics, biguanides
B. Mood stabilizers
C. Antiarrhythmics, anticonvulsants
D. Vascular headache suppressants

Correct answer: B

Rationale: Lithium is classified as a mood stabilizer due to its primary use in managing bipolar disorder, where it helps stabilize mood swings and prevent episodes of mania and depression. While it can have other effects on the body, its main therapeutic role lies in its mood-stabilizing properties. Choices A, C, and D are incorrect as lithium is not classified as antidiabetics, biguanides, antiarrhythmics, anticonvulsants, or vascular headache suppressants. Its main pharmacological class is mood stabilizers.