ATI RN
ATI Pathophysiology Exam 2
1. During the cellular stage of acute inflammation, which type of cells arrive first and in great numbers?
- A. Basophils
- B. Lymphocytes
- C. Neutrophils
- D. Platelets
Correct answer: C
Rationale: During the cellular stage of acute inflammation, neutrophils are the first responders. Neutrophils arrive at the site of injury in large numbers to combat pathogens and remove debris. Basophils and lymphocytes are also involved in the inflammatory response, but they are not the first to arrive. Platelets play a role in hemostasis and blood clotting, rather than being the primary cells involved in the initial inflammatory response.
2. A patient is to be administered an immunization. The serum contains aluminum phosphate. What route is most appropriate to administer this immunization?
- A. Intramuscularly
- B. Subcutaneously
- C. Intravenously
- D. Orally
Correct answer: A
Rationale: The most appropriate route to administer an immunization containing aluminum phosphate is intramuscularly. Aluminum phosphate is commonly used as an adjuvant in vaccines to enhance the immune response. Intramuscular administration allows for the vaccine to be delivered into the muscle tissue, where it can be effectively absorbed by the body's immune cells. Subcutaneous administration is not ideal for vaccines containing aluminum phosphate, as it may not elicit the desired immune response. Intravenous administration is typically reserved for specific medications or situations that require rapid absorption into the bloodstream. Oral administration is not suitable for vaccines containing aluminum phosphate as they would be degraded in the gastrointestinal tract.
3. A patient began antiretroviral therapy several weeks ago for the treatment of HIV, and he has now presented to the clinic for a scheduled follow-up appointment. He states to the nurse, “I've been pretty good about taking all my pills on time, though it was a bit hit and miss over the holiday weekend.” How should the nurse best respond to this patient's statement?
- A. “Remember that if you miss a dose, you need to take a double dose at the next scheduled time.”
- B. “It's acceptable to miss an occasional dose as long as your symptoms don't worsen, but it's important to strive for consistent adherence.”
- C. “Remember that your antiretroviral drugs will only be effective if you take them consistently and as prescribed.”
- D. “If you're not consistent with taking your medications, you're likely to develop more side effects.”
Correct answer: C
Rationale: The correct response is to remind the patient that antiretroviral drugs are most effective when taken consistently and as prescribed. Choice A is incorrect because taking a double dose after missing a dose is not recommended, as it can lead to medication toxicity. Choice B is incorrect as it may give the impression that missing doses is acceptable, which can reduce the effectiveness of the treatment. Choice D is incorrect because while consistency is important, the focus should be on treatment effectiveness rather than side effects.
4. Inflammatory exudates are a combination of several types. Which of the following exudates is composed of a large accumulation of leukocytes?
- A. Serous
- B. Purulent
- C. Fibrinous
- D. Hemorrhagic
Correct answer: B
Rationale: The correct answer is B: Purulent. Purulent exudates, or pus, consist primarily of leukocytes and dead cells, indicating a bacterial infection. Serous exudates contain a thin, watery fluid with few leukocytes. Fibrinous exudates are rich in fibrin and are commonly seen in severe inflammation. Hemorrhagic exudates contain red blood cells due to blood vessel damage.
5. A patient with a history of osteoporosis is prescribed raloxifene (Evista). What is the primary therapeutic action of this medication?
- A. It stimulates the formation of new bone.
- B. It decreases bone resorption and increases bone density.
- C. It increases calcium absorption in the intestines.
- D. It increases the excretion of calcium through the kidneys.
Correct answer: B
Rationale: The correct answer is B: 'It decreases bone resorption and increases bone density.' Raloxifene, as a selective estrogen receptor modulator (SERM), works by reducing bone resorption (breakdown) and maintaining or increasing bone density. This mechanism helps in preventing further bone loss and can even increase bone mass. Choices A, C, and D are incorrect. Raloxifene does not stimulate the formation of new bone (choice A), increase calcium absorption in the intestines (choice C), or increase the excretion of calcium through the kidneys (choice D).
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