ATI RN
Final Exam Pathophysiology
1. What is the action of amphotericin B?
- A. It binds to ergosterol and forms holes in the membrane.
- B. It binds to an enzyme required for the synthesis of ergosterol.
- C. It disrupts the fungal cell walls rather than the cell membrane.
- D. It inhibits glucan synthetase required for glucan synthesis.
Correct answer: A
Rationale: Amphotericin B is an antifungal medication that acts by binding to ergosterol, a component of fungal cell membranes, forming pores that disrupt the integrity of the membrane. This action leads to leakage of cellular contents and ultimately cell death. Choice B is incorrect as amphotericin B does not bind to an enzyme required for the synthesis of ergosterol. Choice C is incorrect as the drug primarily affects the cell membrane rather than the cell wall. Choice D is also incorrect as amphotericin B does not inhibit glucan synthetase.
2. A patient is prescribed medroxyprogesterone acetate (Provera) for the treatment of endometriosis. What should the nurse include in the patient teaching?
- A. Take the medication with food to prevent nausea.
- B. Take the medication at the same time each day to maintain consistent hormone levels.
- C. Avoid prolonged sun exposure while taking this medication.
- D. Discontinue the medication if side effects occur.
Correct answer: B
Rationale: The correct answer is to take the medication at the same time each day to maintain consistent hormone levels and effectiveness. This is crucial for the drug to work optimally. Choice A is incorrect because medroxyprogesterone acetate does not necessarily need to be taken with food to prevent nausea. Choice C is not directly related to the medication's administration and is not a common teaching point for this drug. Choice D is incorrect as discontinuing the medication abruptly can lead to adverse effects and is not recommended without consulting a healthcare provider.
3. What tool is used to determine a client’s level of consciousness?
- A. Magnetic resonance imaging (MRI)
- B. Glasgow Coma Scale (GCS)
- C. Central perfusion pressure (CPP)
- D. Intracranial pressure (ICP) monitoring
Correct answer: B
Rationale: The correct answer is B: Glasgow Coma Scale (GCS). The Glasgow Coma Scale is specifically designed to assess a client's level of consciousness by evaluating verbal, motor, and eye-opening responses. Choice A, Magnetic Resonance Imaging (MRI), is a diagnostic imaging tool that provides detailed images of the body's organs and tissues but is not used to assess consciousness levels. Choice C, Central Perfusion Pressure (CPP), and Choice D, Intracranial Pressure (ICP) monitoring, are related to hemodynamic monitoring and intracranial pressure management, not direct assessment of consciousness.
4. During patient teaching, a young woman asks the nurse the following question: 'If I get pregnant on the 'pill,' should I continue to take it?' What is the nurse's best response?
- A. The pill has no effect on pregnancy.
- B. The pill will cause miscarriage.
- C. This is a personal choice for each woman.
- D. The pill can be harmful to the fetus and should be discontinued.
Correct answer: C
Rationale: The correct answer is 'C: This is a personal choice for each woman.' If a woman becomes pregnant while taking birth control pills, it is generally recommended to discontinue them as they can potentially harm the fetus. However, the decision to continue or discontinue the pill in case of pregnancy is ultimately a personal choice for each woman. Choice A is incorrect because birth control pills are meant to prevent pregnancy, but if a woman becomes pregnant while taking them, the situation changes. Choice B is incorrect because birth control pills do not cause miscarriage; they are intended to prevent pregnancy. Choice D is incorrect because while it is generally advised to discontinue the pill if pregnancy occurs, the decision ultimately depends on the individual circumstances and preferences of the woman.
5. An MRI scan of a 33-year-old female client with new-onset seizures has revealed a lesion on her frontal lobe. Which of the following signs and symptoms would most likely be a direct result of this lesion?
- A. Changes in sensation or movement in the client's limbs
- B. Fluctuations in blood pressure
- C. Changes in speech and reasoning
- D. Increased intracranial pressure
Correct answer: C
Rationale: The correct answer is C: Changes in speech and reasoning. The frontal lobe is responsible for higher cognitive functions, including speech and reasoning. A lesion in this area can lead to difficulties in speech production, language comprehension, and reasoning abilities. Choices A, B, and D are incorrect. Changes in sensation or movement in the client's limbs are more associated with lesions in the motor or sensory cortices of the brain, not the frontal lobe. Fluctuations in blood pressure are often related to autonomic nervous system dysfunction, which is controlled by other brain regions. Increased intracranial pressure is typically seen in conditions like brain tumors or head trauma, not directly related to a frontal lobe lesion.
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