ATI RN
ATI Pathophysiology Quizlet
1. A patient has been prescribed raloxifene (Evista) for the prevention of osteoporosis. What effect should the nurse include in the teaching plan regarding the action of this medication?
- A. Decreases calcium excretion by the kidneys.
- B. Increases intestinal absorption of calcium.
- C. Stimulates bone formation by increasing osteoblast activity.
- D. Selectively binds to estrogen receptors, decreasing bone resorption.
Correct answer: D
Rationale: The correct answer is D: Selectively binds to estrogen receptors, decreasing bone resorption. Raloxifene is a selective estrogen receptor modulator (SERM) that works by binding to estrogen receptors, thereby decreasing bone resorption. This action helps in the prevention and treatment of osteoporosis by preserving bone density. Choices A, B, and C are incorrect because raloxifene does not directly affect calcium excretion by the kidneys, intestinal absorption of calcium, or stimulate bone formation by increasing osteoblast activity.
2. When educating a client about to undergo a pacemaker insertion, the nurse explains the normal phases of cardiac muscle tissue. During the repolarization phase, the nurse will stress that membranes must be repolarized before they can be re-excited. Within the cell, the nurse understands that:
- A. Potassium channels open while sodium channels close, causing repolarization to the resting state.
- B. The influx of calcium is the primary stimulus for the repolarization of cardiac tissue.
- C. Only the electrical activity within the heart will determine when repolarization occurs.
- D. The cell membranes need to stay calm, resulting in muscle tissue becoming refractory.
Correct answer: A
Rationale: During the repolarization phase of cardiac muscle tissue, potassium channels open while sodium channels close. This process is crucial for the cardiac muscle to return to its resting state after depolarization. Potassium moving out of the cell and sodium staying out helps reset the membrane potential and prepare the cell for the next depolarization phase. The influx of calcium is not the primary stimulus for repolarization in cardiac tissue; it is mainly involved in the depolarization phase. While electrical activity within the heart influences repolarization, the specific ion movements described in choice A are what physiologically drive repolarization. Cell membranes need to be in an active state during repolarization, not calm, to facilitate the necessary ion movements for muscle tissue to properly function.
3. When a healthcare professional observes muscle stiffening occurring within 6 to 14 hours after death, the healthcare professional should document this finding as _____ present.
- A. Livor mortis
- B. Gangrene
- C. Algor mortis
- D. Rigor mortis
Correct answer: D
Rationale: The correct answer is D, Rigor mortis. Rigor mortis is the stiffening of muscles after death, typically beginning within 6 to 14 hours. Livor mortis (choice A) refers to the pooling of blood in the lowest tissues causing discoloration, gangrene (choice B) is the death of body tissue due to lack of blood flow, and algor mortis (choice C) is the cooling of the body after death.
4. What serious adverse effect should the nurse monitor for during testosterone therapy?
- A. Testosterone therapy increases the risk of cardiovascular events, so regular monitoring is essential.
- B. Testosterone therapy can cause liver dysfunction, so liver function tests should be monitored regularly.
- C. Testosterone therapy can lead to prostate cancer, so regular screenings are recommended.
- D. Testosterone therapy can lead to bone fractures, so bone density should be monitored.
Correct answer: A
Rationale: The correct answer is A. Testosterone therapy is associated with an increased risk of cardiovascular events. Therefore, the nurse should monitor the patient for cardiovascular complications. While monitoring liver function tests (choice B) and bone density (choice D) may be important in some cases, the primary concern during testosterone therapy is the risk of cardiovascular events. Prostate cancer screenings (choice C) are not directly related to testosterone therapy's adverse effects.
5. What critical point should the nurse include in patient education regarding tamoxifen (Nolvadex) for a patient with breast cancer?
- A. Tamoxifen may increase the risk of venous thromboembolism.
- B. Tamoxifen may cause hot flashes and other menopausal symptoms.
- C. Tamoxifen may cause weight gain and fluid retention.
- D. Tamoxifen may decrease the risk of osteoporosis.
Correct answer: A
Rationale: The correct answer is A. Tamoxifen increases the risk of venous thromboembolism. Patients should be educated about the signs and symptoms of blood clots, such as swelling, redness, and pain in the legs. Choices B, C, and D are incorrect because tamoxifen is not associated with causing hot flashes, weight gain, fluid retention, or decreasing the risk of osteoporosis.
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