a nurse is preparing to administer clindamycin 200 mg by intermittent iv bolus the amount available is clindamycin injection 200 mg in 100 ml 09 sodiu

ATI RN

ATI Pharmacology

1. A healthcare professional is preparing to administer clindamycin 200 mg by intermittent IV bolus. The amount available is clindamycin injection 200 mg in 100 mL 0.9% sodium chloride (0.9% NaCl) to infuse over 30 min. How many mL/hr should the IV pump be set to deliver?

A. 200 mL/hr
B. 150 mL/hr
C. 100 mL/hr
D. 250 mL/hr

Correct answer: A

Rationale: To calculate the flow rate in mL/hr: (Volume in mL / Time in hours) = Flow rate in mL/hr. In this case, (100 mL / 0.5 hr) = 200 mL/hr. Therefore, the IV pump should be set to deliver 200 mL/hr to administer clindamycin 200 mg over 30 minutes. Choice A is correct because it provides the accurate flow rate needed for the administration of the medication. Choices B, C, and D are incorrect as they do not calculate the flow rate correctly based on the volume and time specified in the question.

2. What information should you provide to your patient if they are taking sennosides? Select All That Apply.

A. Sennosides should be used for short-term therapy
B. The medication does not cure hypothyroidism
C. The color of the urine may change to pink, red, violet, yellow, or brown
D. Make sure to use other forms of bowel regulation

Correct answer: A

Rationale: When educating a patient taking sennosides, it is important to emphasize that these laxatives should be used for short-term therapy only. The medication does not address hypothyroidism, so this information is not relevant. Patients should be informed that the color of their urine may change to various colors like pink, red, violet, yellow, or brown, which is a common side effect of sennosides. It is advisable to incorporate other forms of bowel regulation alongside sennosides for optimal bowel health. Choice A is correct as it provides essential guidance on the duration of sennosides use. Choice B is incorrect because sennosides are not used to cure hypothyroidism. Choice C is correct as it highlights a common side effect of sennosides. Choice D is incorrect because it does not specifically relate to sennosides but rather suggests using other forms of bowel regulation in general.

3. Why has an ACE inhibitor been prescribed following an MI?

A. “This medication will lower your potassium level.”
B. “ACE inhibitors have been found to reduce mortality following MI.”
C. “ACE inhibitors are always prescribed with a beta blocker and calcium channel blocker following an MI.”
D. “This medication will treat your hypotension.”

Correct answer: B

Rationale: Following a myocardial infarction (MI), ACE inhibitors are commonly prescribed due to their proven benefit in reducing mortality and improving outcomes post-MI. These medications help by decreasing the workload of the heart, preventing remodeling of the heart chambers, and improving survival rates. While ACE inhibitors may have effects on potassium levels, the primary reason for their prescription post-MI is their mortality-reducing properties.

4. A client with HIV-1 infection is prescribed zidovudine as part of antiretroviral therapy. The nurse should monitor the client for which of the following adverse effects of this medication?

A. Cardiac dysrhythmia
B. Metabolic alkalosis
C. Renal failure
D. Aplastic anemia

Correct answer: D

Rationale: Corrected Rationale: Zidovudine is associated with the development of aplastic anemia, a serious adverse effect characterized by bone marrow suppression. Regular monitoring is essential to detect this side effect early and prevent complications. Cardiac dysrhythmia, metabolic alkalosis, and renal failure are not commonly associated with zidovudine use, making them incorrect choices for adverse effects of this medication.

5. At what amount does Acetaminophen stop effectively controlling pain?

A. Over 1,000 mg
B. 750 mg
C. Over 1,500 mg
D. 150 mg

Correct answer: A

Rationale: Acetaminophen is known to lose its effectiveness in controlling pain beyond a dosage of 1,000 mg. Taking more than 1,000 mg will not provide additional pain relief but can increase the risk of adverse effects. Choice B (750 mg) is incorrect because this amount is within the typical recommended dose range for Acetaminophen. Choice C (Over 1,500 mg) is incorrect as it suggests a higher dose than the point at which Acetaminophen starts to lose its effectiveness. Choice D (150 mg) is too low a dose to effectively control pain for most adults.