ATI RN
Final Exam Pathophysiology
1. A nurse is conducting an assessment on a client who presents with symptoms that are characteristic of amyotrophic lateral sclerosis (ALS). What assessment finding would be expected in this client?
- A. Reduced reflexes in all four limbs
- B. Decreased cognitive function
- C. Involuntary muscle contractions
- D. Hyperreflexia
Correct answer: D
Rationale: The correct answer is D: Hyperreflexia. In amyotrophic lateral sclerosis (ALS), hyperreflexia is a common assessment finding due to the degeneration of upper motor neurons. This results in an overactive reflex response to stimuli. Reduced reflexes in all four limbs (choice A) are not typically seen in ALS; instead, hyperreflexia is more common. Decreased cognitive function (choice B) is not a primary characteristic of ALS. Involuntary muscle contractions (choice C) are more indicative of conditions such as dystonia or myoclonus, not ALS.
2. When the body produces antibodies against its own tissue, the condition is called
- A. Alloimmunity
- B. Opsonization
- C. Autoimmunity
- D. Hypersensitivity
Correct answer: C
Rationale: The correct answer is C, autoimmunity. Autoimmunity refers to the immune system attacking the body's own tissues. Alloimmunity (choice A) is the immune response to tissues of another individual of the same species. Opsonization (choice B) is the process where pathogens are marked for destruction by immune cells. Hypersensitivity (choice D) refers to excessive or inappropriate immune responses.
3. A client with cystic fibrosis is admitted with a pulmonary exacerbation. Which intervention should the nurse prioritize?
- A. Administer a high-calorie, high-protein diet.
- B. Initiate airway clearance techniques.
- C. Encourage the client to maintain an active lifestyle.
- D. Monitor for signs of respiratory distress.
Correct answer: B
Rationale: During a pulmonary exacerbation in cystic fibrosis, the priority intervention is to initiate airway clearance techniques. These techniques help clear mucus from the airways, improving ventilation and reducing the risk of respiratory complications. Administering a high-calorie, high-protein diet is beneficial for overall nutrition but is not the priority during an exacerbation. Encouraging an active lifestyle is important for long-term health but does not address the immediate need for managing exacerbations. Monitoring for signs of respiratory distress is important, but initiating airway clearance techniques takes precedence in the management of pulmonary exacerbations in cystic fibrosis.
4. Which of the following is a characteristic of osteosarcoma?
- A. Slow-growing tumor that begins in the bone marrow
- B. Solitary tumor that most often affects the metaphyseal region of the femur or tibia
- C. An aggressive tumor most often found in the bone marrow of long bones
- D. A tumor that infiltrates the trabeculae in spongy bone and implants in surrounding tissue
Correct answer: C
Rationale: Osteosarcoma is an aggressive bone tumor that most commonly arises in the bone marrow of long bones, such as the femur or tibia. Choice A is incorrect as osteosarcoma is not a slow-growing tumor but rather a fast-growing one. Choice B is incorrect as osteosarcoma is not typically solitary but can involve multiple lesions. Choice D is incorrect as osteosarcoma primarily affects the medullary (marrow) cavity of bones, rather than infiltrating the trabeculae in spongy bone and surrounding tissue.
5. A patient with a history of osteoporosis is prescribed raloxifene (Evista). What is the primary therapeutic effect of this medication?
- A. It stimulates the formation of new bone.
- B. It decreases bone resorption and increases bone density.
- C. It increases calcium absorption in the intestines.
- D. It increases the excretion of calcium through the kidneys.
Correct answer: B
Rationale: The correct answer is B. Raloxifene, such as Evista, works by decreasing bone resorption and increasing bone density. This medication is beneficial in the prevention and treatment of osteoporosis by slowing down the breakdown of bone tissue, thereby reducing the risk of fractures. Choices A, C, and D are incorrect because raloxifene does not directly stimulate the formation of new bone, increase calcium absorption in the intestines, or increase the excretion of calcium through the kidneys.
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