ATI RN
ATI Proctored Pharmacology Test
1. When a client reports urticaria and dyspnea after receiving amoxicillin/clavulanic acid, which medication should be administered first?
- A. Administer epinephrine
- B. Administer albuterol
- C. Administer diphenhydramine
- D. Administer prednisone
Correct answer: A
Rationale: In the scenario described, the client is experiencing symptoms of a severe allergic reaction. The priority intervention is to administer epinephrine. Epinephrine acts quickly to reverse the effects of the allergic reaction and can be life-saving in cases of anaphylaxis. Albuterol is used for bronchodilation and may help with respiratory symptoms but is not the first-line treatment for anaphylaxis. Diphenhydramine and prednisone are used for allergic reactions but are not as rapid-acting as epinephrine and should be considered after administering epinephrine in this situation.
2. What symptom would alert the healthcare professional to hold Albuterol and notify a healthcare professional immediately?
- A. Insomnia
- B. Paradoxical bronchospasm
- C. Nausea
- D. Headache
Correct answer: B
Rationale: If a patient experiences paradoxical bronchospasm after taking Albuterol, the medication should be withheld, and a healthcare professional should be notified immediately. Paradoxical bronchospasm is a serious adverse reaction where the airways constrict instead of dilating, leading to breathing difficulties. This condition requires prompt medical attention to assess and manage the patient's respiratory status. The other options, insomnia, nausea, and headache, are not typically associated with the need to hold Albuterol and notify a healthcare professional immediately.
3. A client prescribed Warfarin is receiving discharge instructions from a nurse. Which of the following herbal supplements should the nurse instruct the client to avoid?
- A. St. John's wort
- B. Echinacea
- C. Garlic
- D. Ginseng
Correct answer: A
Rationale: St. John's wort can reduce the effectiveness of Warfarin by interacting with its metabolism pathways, potentially leading to decreased anticoagulant effects. Therefore, clients on Warfarin therapy should avoid St. John's wort. While echinacea, garlic, and ginseng are also herbal supplements that can interact with Warfarin, St. John's wort is particularly known for its significant impact on Warfarin metabolism. Echinacea may increase the risk of bleeding when taken with Warfarin, garlic may potentiate the anticoagulant effects of Warfarin, and ginseng may also increase the risk of bleeding. However, St. John's wort is the most crucial to avoid due to its significant impact on Warfarin metabolism.
4. A client is starting a new prescription for ferrous sulfate. Which of the following instructions should the nurse include?
- A. Take the medication with meals.
- B. Take the medication on an empty stomach.
- C. Take the medication with orange juice to enhance absorption.
- D. Take the medication with a full glass of milk.
Correct answer: C
Rationale: The correct answer is C: 'Take the medication with orange juice to enhance absorption.' Taking ferrous sulfate with orange juice helps enhance the absorption of iron due to the ascorbic acid present in the orange juice, which aids in iron absorption. This combination can help improve the effectiveness of the medication. Choice A, taking the medication with meals, may reduce gastrointestinal side effects but does not specifically enhance absorption. Choice B, taking the medication on an empty stomach, may lead to better absorption but can also increase the risk of gastrointestinal side effects. Choice D, taking the medication with a full glass of milk, is incorrect because calcium in milk can inhibit the absorption of iron.
5. A client has a new prescription for a Nitroglycerin transdermal patch. Which of the following instructions should the nurse include?
- A. Apply the patch to the same site each day.
- B. Remove the patch at night.
- C. Cover the patch with a heating pad.
- D. Apply the patch to a hairless area of skin.
Correct answer: D
Rationale: The correct instruction is to apply the Nitroglycerin transdermal patch to a hairless area of skin. This is important for proper absorption of the medication. Additionally, rotating the patch to different sites each day helps prevent skin irritation and ensures optimal therapeutic effect. Applying the patch to the same site each day can lead to skin irritation or tolerance development. Removing the patch at night is not necessary as the patch is typically worn continuously to provide a consistent level of medication. Covering the patch with a heating pad is contraindicated as it can increase drug absorption, potentially leading to adverse effects.
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