ATI RN
ATI Pathophysiology Quizlet
1. A 57-year-old male presents to his primary care provider with a red face, hands, feet, ears, headache, and drowsiness. A blood smear reveals an increased number of erythrocytes, indicating:
- A. Leukemia
- B. Sideroblastic anemia
- C. Hemosiderosis
- D. Polycythemia vera
Correct answer: D
Rationale: In this case, the symptoms of a red face, hands, feet, ears, headache, and drowsiness along with an increased number of erythrocytes in the blood smear are indicative of polycythemia vera. This condition is characterized by the overproduction of red blood cells, leading to symptoms related to increased blood volume and viscosity. Leukemia (Choice A) is a cancer of the blood and bone marrow, but the presentation described here is more suggestive of polycythemia vera. Sideroblastic anemia (Choice B) is characterized by abnormal iron deposits in erythroblasts, not an increased number of erythrocytes. Hemosiderosis (Choice C) refers to abnormal accumulation of iron in the body, not an increase in red blood cells as seen in polycythemia vera.
2. Which of the following is a sign of hypoglycemia?
- A. Rapid, deep breathing
- B. Increased urination
- C. Weakness and confusion
- D. High blood pressure
Correct answer: C
Rationale: The correct answer is C: Weakness and confusion. Hypoglycemia is characterized by low blood sugar levels, leading to inadequate glucose supply to the brain, resulting in symptoms like weakness and confusion. Choices A, B, and D are incorrect. Rapid, deep breathing is not typically a sign of hypoglycemia but can be seen in other conditions like respiratory issues. Increased urination is more commonly associated with conditions like diabetes mellitus, while high blood pressure is not a typical sign of hypoglycemia.
3. What is the cause of swelling during acute inflammation?
- A. Collagenase
- B. Fluid exudate
- C. Lymphocytic margination
- D. Anaerobic glycolysis
Correct answer: B
Rationale: Swelling during acute inflammation is primarily caused by the accumulation of fluid exudate in the affected tissues. This fluid exudate contains proteins and cells that leak from blood vessels due to increased vascular permeability. Collagenase (Choice A) is an enzyme that breaks down collagen and is not directly responsible for swelling. Lymphocytic margination (Choice C) is the process where white blood cells line up along the blood vessel walls, which does not directly cause swelling. Anaerobic glycolysis (Choice D) is a metabolic process that occurs in the absence of oxygen and is not related to the mechanism of swelling in acute inflammation.
4. Inflammatory exudates are a combination of several types. Which of the following exudates is composed of a large accumulation of leukocytes?
- A. Serous
- B. Purulent
- C. Fibrinous
- D. Hemorrhagic
Correct answer: B
Rationale: The correct answer is B: Purulent. Purulent exudates, or pus, consist primarily of leukocytes and dead cells, indicating a bacterial infection. Serous exudates contain a thin, watery fluid with few leukocytes. Fibrinous exudates are rich in fibrin and are commonly seen in severe inflammation. Hemorrhagic exudates contain red blood cells due to blood vessel damage.
5. A patient is prescribed tadalafil (Cialis) for erectile dysfunction. What condition would contraindicate the use of this medication?
- A. History of hypertension
- B. Use of nitrates
- C. Use of antihypertensive medications
- D. History of peptic ulcer disease
Correct answer: B
Rationale: The correct answer is B: 'Use of nitrates.' Tadalafil (Cialis) is contraindicated in patients using nitrates due to the risk of severe hypotension. Nitrates and tadalafil both cause vasodilation, leading to a synergistic effect that can result in a dangerous drop in blood pressure. Choices A, C, and D are incorrect because a history of hypertension, the use of antihypertensive medications, and a history of peptic ulcer disease are not direct contraindications for tadalafil use.
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