which of the following are not treated with methotrexate
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Nursing Elites

ATI RN

ATI Pharmacology Proctored

1. Which of the following conditions is not treated with Methotrexate?

Correct answer: D

Rationale: The correct answer is D. Methotrexate is not typically used to treat rheumatic fever, which is more commonly managed with antibiotics to eradicate the underlying infection. Methotrexate is commonly used in the treatment of conditions like sarcomas, leukemias, and ectopic pregnancies due to its anti-inflammatory and anti-cancer properties.

2. What is a desired outcome of the drug Phenytoin?

Correct answer: C

Rationale: The correct answer is C: Decrease or cessation of seizures without excessive sedation. Phenytoin is primarily used as an antiepileptic medication to manage and prevent seizures. It does not directly impact symptoms of PTSD (Choice A), resolution of signs of infection (Choice B), or prevention or relief of bronchospasm (Choice D). Therefore, the desired outcome of Phenytoin is to control seizures effectively while avoiding excessive sedation.

3. A client is taking lisinopril. Which of the following outcomes indicates a therapeutic effect of the medication?

Correct answer: A

Rationale: The therapeutic effect of lisinopril, an ACE inhibitor, is indicated by a decrease in blood pressure. Lisinopril works by relaxing blood vessels, leading to a reduction in blood pressure. Monitoring and achieving a decrease in blood pressure is a key outcome when managing hypertension with lisinopril. Choices B, C, and D are incorrect because lisinopril is not intended to increase HDL cholesterol, prevent bipolar manic episodes, or improve sexual function. Therefore, the correct outcome indicating the therapeutic effect of lisinopril is a decrease in blood pressure.

4. When educating a client prescribed Rifampin, which instruction should the nurse provide?

Correct answer: A

Rationale: The correct instruction for a client prescribed Rifampin is to expect orange discoloration of urine. Rifampin is known to cause harmless discoloration of bodily fluids, including urine, which is a common side effect of this medication. It is important for the nurse to educate the client about this expected side effect to prevent unnecessary concern or discontinuation of the medication. Choices B, C, and D are incorrect because Rifampin does not require specific dietary considerations like taking it with food or increasing dairy intake. Furthermore, itching is not a common side effect that would necessitate immediate discontinuation of Rifampin.

5. What are the Therapeutic Effects of Lithium?

Correct answer: A

Rationale: The therapeutic effect of lithium is that it prevents or decreases the incidence of acute manic episodes in patients with bipolar disorder. Lithium is commonly used as a mood stabilizer in the treatment of bipolar disorder due to its ability to reduce the frequency and severity of manic episodes. Choices B, C, and D are incorrect as lithium is not used for the maintenance of blood glucose, control of hyperglycemia in diabetic patients, or to diminish seizure activity. These effects are not associated with the use of lithium as a medication.

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