ATI RN
ATI Pathophysiology
1. When the body produces antibodies against its own tissue, the condition is called
- A. Alloimmunity
- B. Opsonization
- C. Autoimmunity
- D. Hypersensitivity
Correct answer: C
Rationale: The correct answer is C, autoimmunity. Autoimmunity refers to the immune system attacking the body's own tissues. Alloimmunity (choice A) is the immune response to tissues of another individual of the same species. Opsonization (choice B) is the process where pathogens are marked for destruction by immune cells. Hypersensitivity (choice D) refers to excessive or inappropriate immune responses.
2. A nurse is providing education to a patient starting hormone replacement therapy (HRT) for menopausal symptoms. What should the nurse emphasize regarding the long-term risks associated with HRT?
- A. HRT may increase the risk of cardiovascular events, including heart attack and stroke.
- B. HRT may decrease the risk of osteoporosis.
- C. HRT may improve mood and energy levels.
- D. HRT may decrease the risk of breast cancer.
Correct answer: A
Rationale: HRT is associated with an increased risk of cardiovascular events, including heart attack and stroke, particularly with long-term use.
3. Which of the following is a factor that leads to increased risk for dehydration in the elderly?
- A. More insensible losses
- B. Increase in muscle mass
- C. Decline in kidney function
- D. Decrease in fat
Correct answer: C
Rationale: The correct answer is C: Decline in kidney function. As people age, their kidneys may not work as effectively in conserving water and concentrating urine, leading to a higher risk of dehydration. Choice A is incorrect because more insensible losses do not directly relate to an increased risk of dehydration in the elderly. Choice B, an increase in muscle mass, is not a factor that leads to dehydration. Choice D, a decrease in fat, is also not a direct factor contributing to dehydration in the elderly.
4. How will taking an oral contraceptive affect the physiologically of an insulin-dependent diabetic patient?
- A. Increase risk of hypoglycemia
- B. Increase heart rate
- C. Increase blood glucose
- D. Increase risk of metabolic alkalosis
Correct answer: C
Rationale: Taking an oral contraceptive can lead to an increase in blood glucose levels in insulin-dependent diabetic patients. This occurs due to the hormonal changes induced by the contraceptive, which can impact insulin sensitivity. Therefore, diabetic patients need to closely monitor their blood glucose levels when starting an oral contraceptive to prevent complications. The other choices are incorrect as oral contraceptives do not typically lead to an increase in heart rate, risk of hypoglycemia, or risk of metabolic alkalosis in this context.
5. Which of the following statements describes an active cellular membrane exchange process?
- A. Sodium moving out of cells and potassium moving into cells
- B. The movement of water from an area of low solute concentration to an area of high solute concentration
- C. The movement of insulin using a protein to travel across the cell membrane
- D. Oxygen moving across the pulmonary capillaries to an area of high carbon dioxide
Correct answer: A
Rationale: The correct answer is A. In active transport, energy is expended to move substances against their concentration gradient. Sodium moving out of cells and potassium moving into cells is an example of active transport because it requires energy to pump these ions across the cell membrane against their concentration gradients. Choices B, C, and D describe passive processes where substances move along their concentration gradients without the input of energy.
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