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ATI Pharmacology Test Bank
1. When using Nitroglycerine (transdermal), how many hours should you be nitrate-free each day?
- A. 1-2 hours
- B. 5-10 hours
- C. 3-4 hours
- D. 10-12 hours
Correct answer: D
Rationale: When using Nitroglycerine (transdermal), it should be applied for 10-12 hours per day to ensure its effectiveness. A nitrate-free period within the day is essential to prevent the development of tolerance to the medication.
2. A client has a new prescription for Efavirenz, an NNRTI. Which of the following instructions should the nurse include?
- A. Take this medication at bedtime to prevent drowsiness.
- B. Take this medication with a glass of milk.
- C. Take this medication with a glass of juice.
- D. Take this medication at the same time every day.
Correct answer: A
Rationale: The correct instruction is to take Efavirenz at bedtime to prevent drowsiness and manage central nervous system side effects like dizziness and vivid dreams. While it is important to take the medication at the same time daily for consistent blood levels, the emphasis should be on bedtime to minimize the impact of these side effects. Choices B and C suggesting taking the medication with milk or juice are incorrect and not relevant to optimizing Efavirenz therapy.
3. A healthcare professional is preparing to administer Filgrastim for the first time to a client who has just undergone a bone marrow transplant. Which of the following interventions is appropriate?
- A. Administer subcutaneously in a large muscle mass to prevent injury.
- B. Ensure that the medication is kept at room temperature until just prior to administration.
- C. Invert vial gently to mix well before withdrawing dose.
- D. Discard vial after removing one dose of the medication.
Correct answer: D
Rationale: The correct intervention when preparing to administer Filgrastim is to discard the vial after removing one dose of the medication. This practice helps prevent contamination and ensures the medication's effectiveness. Reusing the vial can lead to contamination and compromise the sterility of the medication, putting the client at risk. Therefore, it is crucial to follow proper aseptic technique and discard the vial after withdrawing the prescribed dose.
4. Which of the following is not a common effect of Midazolam?
- A. Amnesia
- B. Decreased respiratory function
- C. Anesthetic
- D. Dizziness
Correct answer: D
Rationale: Midazolam is a benzodiazepine commonly used for its sedative, anxiolytic, and amnestic effects. While dizziness can be a side effect of Midazolam, it is not a primary or common effect. Therefore, the correct answer is D, as it deviates from the typical effects associated with Midazolam.
5. A healthcare professional is admitting a toddler to the hospital after an Acetaminophen overdose. Which of the following medications should the healthcare professional anticipate administering to this client?
- A. Acetylcysteine
- B. Pegfilgrastim
- C. Misoprostol
- D. Naltrexone
Correct answer: A
Rationale: The correct answer is Acetylcysteine. Acetylcysteine is the antidote for acetaminophen overdose. It works by replenishing glutathione, which is depleted in cases of acetaminophen overdose, thus preventing liver damage. Pegfilgrastim is a medication used to stimulate white blood cell production, misoprostol is a medication used to prevent gastric ulcers, and naltrexone is used in the management of opioid addiction and alcohol dependence, which are not indicated in the scenario described.
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