ATI RN
ATI Proctored Pharmacology 2023
1. What should you monitor when administering Clopidogrel to a patient?
- A. Signs of thrombotic thrombocytopenic purpura
- B. Bleeding during therapy
- C. CBC with differential and platelet count
- D. All of the above
Correct answer: D
Rationale: When administering Clopidogrel, it is crucial to monitor for signs of thrombotic thrombocytopenic purpura, bleeding during therapy, and changes in CBC with differential and platelet count. Thrombotic thrombocytopenic purpura is a rare but serious condition associated with Clopidogrel use, characterized by microangiopathic hemolytic anemia, thrombocytopenia, neurological symptoms, fever, and renal dysfunction. Monitoring for signs of thrombotic thrombocytopenic purpura is essential to detect this potentially life-threatening condition early. Monitoring for bleeding helps to assess the risk of hemorrhagic events, a known side effect of Clopidogrel. Additionally, regular monitoring of CBC with differential and platelet count is necessary to evaluate the drug's impact on blood cell counts and detect any abnormalities that may require intervention. Therefore, monitoring all these parameters is vital to ensure patient safety and appropriate management during Clopidogrel therapy.
2. A healthcare professional is preparing to administer clindamycin 200 mg by intermittent IV bolus. The amount available is clindamycin injection 200 mg in 100 mL 0.9% sodium chloride (0.9% NaCl) to infuse over 30 min. How many mL/hr should the IV pump be set to deliver?
- A. 200 mL/hr
- B. 150 mL/hr
- C. 100 mL/hr
- D. 250 mL/hr
Correct answer: A
Rationale: To calculate the flow rate in mL/hr: (Volume in mL / Time in hours) = Flow rate in mL/hr. In this case, (100 mL / 0.5 hr) = 200 mL/hr. Therefore, the IV pump should be set to deliver 200 mL/hr to administer clindamycin 200 mg over 30 minutes. Choice A is correct because it provides the accurate flow rate needed for the administration of the medication. Choices B, C, and D are incorrect as they do not calculate the flow rate correctly based on the volume and time specified in the question.
3. A patient states he experiences anxiety and has panic attacks at least once a week. What might be helpful for this patient?
- A. Phenytoin (Dilantin)
- B. Lithium
- C. Alprazolam (Xanax)
- D. Spironolactone
Correct answer: C
Rationale: Alprazolam (Xanax) is a medication commonly prescribed to treat anxiety disorders and panic attacks. It belongs to the class of medications known as benzodiazepines, which work by enhancing the effects of gamma-aminobutyric acid (GABA) in the brain to produce a calming effect. Phenytoin is an antiepileptic drug, not typically used for anxiety or panic attacks. Lithium is primarily used to treat bipolar disorder, not anxiety. Spironolactone is a diuretic primarily used to treat conditions like high blood pressure and heart failure, not anxiety or panic attacks.
4. A healthcare provider is providing discharge instructions to a client who is prescribed Prednisone. Which of the following dietary instructions should the healthcare provider include?
- A. Increase your intake of potassium-rich foods.
- B. Increase your intake of dairy products.
- C. Avoid foods high in vitamin K.
- D. Decrease your intake of protein.
Correct answer: A
Rationale: The correct answer is to increase the intake of potassium-rich foods (Choice A). Prednisone can cause potassium depletion, so clients should increase their intake of foods such as bananas, oranges, and spinach. Potassium-rich foods help maintain electrolyte balance and prevent complications associated with low potassium levels, such as muscle weakness and irregular heartbeats. Choices B, C, and D are incorrect because increasing dairy products (Choice B) or avoiding foods high in vitamin K (Choice C) are not specifically related to Prednisone therapy. Decreasing protein intake (Choice D) is also not necessary in this case.
5. When teaching a client with a prescription for Vancomycin, which instruction should the nurse include?
- A. Expect red man syndrome during treatment.
- B. Take the medication with a full glass of water.
- C. Increase your intake of potassium-rich foods.
- D. Monitor for hearing loss while taking this medication.
Correct answer: D
Rationale: The correct answer is D. Vancomycin is known to cause ototoxicity, which can result in hearing loss. Therefore, it is important for clients to monitor for any changes in their hearing while taking this medication and promptly report any issues to their healthcare provider for further evaluation and management. Choices A, B, and C are incorrect because red man syndrome is associated with rapid infusion of Vancomycin, not a common side effect during treatment; taking the medication with a full glass of water is a general instruction for many medications but not specific to Vancomycin; and increasing potassium-rich foods is not directly related to Vancomycin therapy.
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