ATI RN
ATI Pharmacology Test Bank
1. What is the therapeutic use of Phenytoin?
- A. Replacement in hypothyroidism to restore normal hormonal balance
- B. Diminished accumulation of acid in the gastric lumen with lessened gastroesophageal reflux
- C. Diminished seizure activity, termination of ventricular arrhythmias
- D. Prevention of thrombus formation, prevention of extension of existing thrombi
Correct answer: C
Rationale: Phenytoin is primarily used to diminish seizure activity and is effective in terminating ventricular arrhythmias. It works by stabilizing neuronal membranes, reducing repetitive neuronal firing, and limiting the spread of seizure activity in the brain. While phenytoin does not have a direct role in preventing thrombus formation or extending existing thrombi, it is crucial in managing seizures and certain arrhythmias.
2. A client has a new prescription for Pancrelipase for chronic pancreatitis. Which of the following instructions should be included by the nurse?
- A. Take the medication with meals and snacks.
- B. Chew the tablet thoroughly before swallowing.
- C. Take the medication 1 hour before meals.
- D. Expect the stool to be yellow.
Correct answer: A
Rationale: The correct instruction for taking Pancrelipase is to take it with meals and snacks to aid in the digestion of fats, proteins, and carbohydrates. This helps optimize the effectiveness of the medication in managing chronic pancreatitis. Choice B is incorrect because Pancrelipase should not be chewed but swallowed whole. Choice C is incorrect as the medication should be taken with meals. Choice D is incorrect because while Pancrelipase can cause stool changes, yellow stool is not an expected outcome.
3. A client has been prescribed Aspirin for prevention of cardiovascular disease. Which of the following findings indicates the medication is effective?
- A. The client has a decrease in troponin levels.
- B. The client has a regular heart rhythm.
- C. The client experiences a decrease in episodes of angina.
- D. The client's blood pressure remains stable.
Correct answer: C
Rationale: The correct answer is C. A decrease in episodes of angina is an indicator of Aspirin's effectiveness in preventing cardiovascular events. Aspirin works by inhibiting platelet aggregation, thereby reducing the formation of blood clots that could lead to angina episodes or more severe cardiovascular complications. Choices A, B, and D are incorrect because troponin levels, heart rhythm, and blood pressure are not direct indicators of Aspirin's effectiveness in preventing cardiovascular events.
4. A client is receiving daily doses of Oprelvekin. Which of the following laboratory values should the nurse monitor to determine the effectiveness of this medication?
- A. Hemoglobin
- B. Absolute neutrophil count
- C. Platelet count
- D. Total white blood cell count
Correct answer: C
Rationale: The nurse should monitor the platelet count to determine the effectiveness of Oprelvekin. The expected outcome for this medication is a platelet count greater than 50,000/mm^3. Oprelvekin is a medication used to stimulate platelet production, making platelet count a crucial parameter to assess its effectiveness. Monitoring hemoglobin, absolute neutrophil count, or total white blood cell count is not specifically related to the action or effectiveness of Oprelvekin.
5. A client has a new prescription for Docusate Sodium. Which of the following instructions should the nurse include?
- A. Take the medication with a full glass of water.
- B. Expect results within 30 minutes.
- C. Take this medication at bedtime.
- D. Avoid taking this medication with food.
Correct answer: A
Rationale: The correct instruction for a client prescribed Docusate Sodium is to take the medication with a full glass of water. Docusate sodium is a stool softener, and taking it with water helps to soften the stool and make bowel movements easier. Adequate fluid intake is crucial when taking stool softeners to prevent constipation. Choices B, C, and D are incorrect. B is incorrect because the effects of Docusate Sodium may not be immediate, and it may take a couple of days for the stool softener to work. Choice C is incorrect as there is no specific requirement to take this medication at bedtime. Choice D is incorrect because there is no instruction to avoid taking Docusate Sodium with food.
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