ATI RN
ATI Proctored Pharmacology Test
1. A client has a new prescription for Sulfasalazine for the treatment of Crohn's disease. Which of the following instructions should the nurse include?
- A. Expect orange-yellow discoloration of urine and skin.
- B. Take the medication with food.
- C. Do not discontinue the medication if a sore throat occurs.
- D. Avoid prolonged exposure to sunlight.
Correct answer: A
Rationale: The correct answer is A: 'Expect orange-yellow discoloration of urine and skin.' Sulfasalazine can cause this harmless side effect, which does not require discontinuation of the medication. Option B is incorrect because Sulfasalazine is usually taken with food to minimize gastrointestinal side effects. Option C is incorrect as a sore throat is not a common reason to stop the medication. Option D is not directly related to the side effects of Sulfasalazine.
2. A client has a new prescription for Ondansetron. Which of the following statements should the nurse include?
- A. Take the medication 30 minutes before chemotherapy.
- B. Expect your urine to turn orange.
- C. Increase your intake of high-fiber foods.
- D. Avoid drinking grapefruit juice.
Correct answer: A
Rationale: The correct answer is A: 'Take the medication 30 minutes before chemotherapy.' Ondansetron, an antiemetic, should be taken before chemotherapy to prevent nausea and vomiting. Taking it 30 minutes before chemotherapy ensures the medication is most effective in controlling chemotherapy-induced nausea and vomiting. Choices B, C, and D are incorrect. Option B is unrelated to Ondansetron, option C is not necessary for this medication, and option D does not interact with Ondansetron but is relevant for other medications.
3. A client is receiving long-term aspirin therapy. The healthcare provider should monitor the client for which of the following complications?
- A. Hemorrhagic stroke
- B. Thromboembolic stroke
- C. Iron deficiency anemia
- D. Neutropenia
Correct answer: A
Rationale: The correct answer is A: Hemorrhagic stroke. Long-term aspirin therapy can lead to hemorrhagic stroke due to its antiplatelet effects, which increase the risk of bleeding. Aspirin inhibits platelet aggregation, which can predispose the individual to bleeding complications, including hemorrhagic stroke. Choices B, C, and D are incorrect because aspirin therapy is more likely to cause bleeding complications rather than thromboembolic events, iron deficiency anemia, or neutropenia.
4. A client has been prescribed Aspirin for prevention of cardiovascular disease. Which of the following findings indicates the medication is effective?
- A. The client has a decrease in troponin levels.
- B. The client has a regular heart rhythm.
- C. The client experiences a decrease in episodes of angina.
- D. The client's blood pressure remains stable.
Correct answer: C
Rationale: The correct answer is C. A decrease in episodes of angina is an indicator of Aspirin's effectiveness in preventing cardiovascular events. Aspirin works by inhibiting platelet aggregation, thereby reducing the formation of blood clots that could lead to angina episodes or more severe cardiovascular complications. Choices A, B, and D are incorrect because troponin levels, heart rhythm, and blood pressure are not direct indicators of Aspirin's effectiveness in preventing cardiovascular events.
5. A client has a new prescription for Lisinopril. Which of the following adverse effects should the nurse monitor?
- A. Dry cough
- B. Weight gain
- C. Diarrhea
- D. Nausea
Correct answer: A
Rationale: The correct answer is 'Dry cough.' Lisinopril, an ACE inhibitor, commonly causes a persistent dry cough as an adverse effect. If the client experiences this, it is important to notify the healthcare provider for further evaluation and management.
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