multiple sclerosis manifests as asymmetrical and in different parts of the body because

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Pathophysiology Practice Questions

1. Multiple sclerosis manifests as asymmetrical and in different parts of the body because:

A. Autoreactive lymphocytes are causing diffuse patchy damage to the myelin sheath in the central nervous system.
B. Acetylcholine receptors are destroyed by immunoglobulin G.
C. Autoreactive T lymphocytes cause progressive loss of neurons in the substantia nigra.
D. Cortical motor cells degenerate.

Correct answer: A

Rationale: The correct answer is A. Multiple sclerosis is characterized by the immune system attacking the myelin sheath in the central nervous system. This attack leads to patchy damage on the myelin sheath, resulting in asymmetrical neurological symptoms. Choices B, C, and D are incorrect because they do not accurately describe the pathophysiology of multiple sclerosis. In multiple sclerosis, it is the autoreactive lymphocytes that target and damage the myelin sheath, not acetylcholine receptors, T lymphocytes, or cortical motor cells.

2. A patient with a history of breast cancer is being prescribed tamoxifen (Nolvadex). What is a critical point the nurse should include in the patient education?

A. Tamoxifen may increase the risk of venous thromboembolism.
B. Tamoxifen may decrease the risk of osteoporosis.
C. Tamoxifen may cause hot flashes and other menopausal symptoms.
D. Tamoxifen may cause weight gain and fluid retention.

Correct answer: A

Rationale: The correct answer is A. Tamoxifen increases the risk of venous thromboembolism, so patients should be educated about the signs and symptoms of blood clots. Choice B is incorrect because tamoxifen does not decrease the risk of osteoporosis. Choice C is incorrect as tamoxifen may cause hot flashes and other menopausal symptoms but this is not the critical point for patient education. Choice D is incorrect as tamoxifen may cause weight gain and fluid retention, but it is not the critical point that the nurse should focus on in patient education.

3. A patient arrives at her follow-up appointment 1 month post-hysterectomy and complains to the nurse that her scars do not seem to be healing properly. Upon inspection, the nurse notices that the scars are raised but still within the boundaries of the original incisions. The nurse tells the patient this kind of dysfunctional wound healing is called:

A. Hypertrophic scarring
B. Dehiscence
C. Contracture
D. A keloid

Correct answer: A

Rationale: Hypertrophic scarring occurs when a scar is raised but remains within the boundaries of the original wound, unlike keloids, which extend beyond the wound edges. Dehiscence refers to the separation of wound edges, while contracture involves the tightening or constriction of a scar, leading to limited mobility.

4. A male patient receiving androgen therapy is concerned about the risk of prostate cancer. What should the nurse explain about this risk?

A. Finasteride has been shown to lower the risk of developing prostate cancer.
B. Finasteride does not affect the risk of prostate cancer, so regular screening is unnecessary.
C. Finasteride may increase the risk of developing prostate cancer, so regular screenings are recommended.
D. Finasteride has no effect on the risk of prostate cancer, so regular screenings are unnecessary.

Correct answer: A

Rationale: The correct answer is A. Finasteride has been shown to lower the risk of developing prostate cancer. However, regular screenings are still recommended to monitor for any potential issues. Choice B is incorrect because finasteride has been associated with a decreased risk of prostate cancer, making regular screenings important. Choice C is incorrect as finasteride is not known to increase the risk of developing prostate cancer. Choice D is incorrect as finasteride has shown a protective effect against prostate cancer, but regular screenings are still necessary to ensure early detection and monitoring.

5. Which of the following accurately describes the pathophysiology of asthma?

A. Chronic inflammation of the bronchial lining
B. Narrowing of the airway due to bronchoconstriction
C. Damage to alveoli reducing lung elasticity
D. Overproduction of mucus by the goblet cells

Correct answer: B

Rationale: The correct answer is B: "Narrowing of the airway due to bronchoconstriction." In asthma, there is an inflammatory response that leads to bronchoconstriction, causing the airways to narrow and making it difficult to breathe. Choice A is incorrect as chronic inflammation is a feature of asthma but not the primary pathophysiological mechanism. Choice C is incorrect as damage to alveoli is more characteristic of conditions like emphysema. Choice D is incorrect as overproduction of mucus is a feature of chronic bronchitis, not asthma.