ATI RN
Pathophysiology Final Exam
1. An oncology nurse is providing care for an adult patient who is currently immunocompromised. The nurse is aware of the physiology involved in hematopoiesis and immune function, including the salient role of cytokines. What is the primary role of cytokines in maintaining homeostasis?
- A. Cytokines perform phagocytosis in response to bacterial and protozoal infections.
- B. Cytokines perform a regulatory role in the development of diverse blood cells.
- C. Cytokines play a significant role in the formation of all blood cells.
- D. Cytokines are produced in response to the presence of antibodies.
Correct answer: B
Rationale: The primary role of cytokines in maintaining homeostasis is to perform a regulatory function in the development of diverse blood cells. Cytokines act as signaling molecules that regulate the immune response and hematopoiesis. Choice A is incorrect because cytokines do not perform phagocytosis; they regulate immune responses. Choice C is incorrect because while cytokines are involved in the formation of some blood cells, they are not considered the basic 'building blocks' of all blood cells. Choice D is incorrect because cytokines are not formed in response to antibodies, but rather play a role in the immune response to various stimuli.
2. Which of the following factors are known to contribute to an individual's ability to adapt to stress? (Select ONE that does not apply.)
- A. Ethnicity
- B. Age
- C. Socioeconomic status
- D. Gender
Correct answer: A
Rationale: The correct factors that contribute to an individual's ability to adapt to stress are age, socioeconomic status, and gender. Age can influence coping mechanisms and resilience. Socioeconomic status can impact access to resources and support systems. Gender differences can also play a role in how individuals experience and manage stress. Ethnicity, while important in other contexts, is not directly mentioned in the provided rationale and is not one of the factors listed as contributing to an individual's ability to adapt to stress.
3. During a follow-up visit, a patient being treated for latent tuberculosis mentions inconsistent drug intake. What should subsequent health education focus on?
- A. The importance of adhering to the treatment regimen to reduce adverse effects
- B. The necessity of consistently taking the prescribed drugs for TB cure
- C. Matching drug dosages carefully to signs and symptoms
- D. The consequence of nonadherence leading to antiretroviral use
Correct answer: B
Rationale: The correct answer is B because consistent intake of prescribed drugs is crucial for curing tuberculosis. By emphasizing the necessity of following the treatment plan, the patient is more likely to achieve a successful outcome. Choice A is incorrect because it focuses on the risk of adverse effects rather than the primary goal of TB cure. Choice C is incorrect as it does not address the issue of inconsistent drug intake. Choice D is also incorrect as it introduces a different treatment (antiretrovirals) not relevant to latent tuberculosis.
4. After a thoracentesis on a client with a pleural effusion, which nursing intervention is most important post-procedure?
- A. Monitor for signs of infection.
- B. Assess for signs of bleeding or hematoma.
- C. Monitor vital signs and respiratory status.
- D. Instruct the client to rest and limit physical activity.
Correct answer: B
Rationale: The correct answer is to assess for signs of bleeding or hematoma. After a thoracentesis, it is crucial to monitor for any bleeding or hematoma formation at the puncture site, as this can lead to complications. Monitoring for signs of infection (Choice A) is essential but is usually a delayed concern compared to the immediate risk of bleeding post-procedure. While monitoring vital signs and respiratory status (Choice C) is important, assessing for bleeding takes precedence to address any immediate complications. Instructing the client to rest and limit physical activity (Choice D) is relevant for general post-procedure care but is not the most critical intervention in this scenario.
5. What condition can be caused by an excessive amount of growth hormone released by the pituitary gland in childhood?
- A. Acromegaly
- B. Gigantism
- C. Syndrome of inappropriate antidiuretic hormone
- D. Dwarfism
Correct answer: B
Rationale: Gigantism is the correct answer. It is a condition caused by excessive growth hormone release before the epiphyseal plates close, leading to abnormal growth. Acromegaly (choice A) is caused by excess growth hormone after the epiphyseal plates close, resulting in enlargement of bones and tissues. Syndrome of inappropriate antidiuretic hormone (choice C) is characterized by the excessive release of antidiuretic hormone, leading to water retention and dilutional hyponatremia. Dwarfism (choice D) is a condition characterized by significantly below-average height.
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