ATI RN
ATI Pathophysiology Final Exam
1. A homeless man was screened for tuberculosis (TB) during a health consultation at a shelter, and the results indicate latent TB. The community health nurse who is liaising with the providers of the shelter would anticipate what component of this man's plan of care?
- A. The man will undergo conservative treatment for TB using adjuvant medications.
- B. The man will be treated for TB using first-line antitubercular drugs.
- C. The man will be monitored closely to determine if treatment is necessary.
- D. The man will be screened again in 10 to 12 weeks to determine if he has developed active TB.
Correct answer: B
Rationale: The correct answer is B. When a patient is diagnosed with latent TB infection, the standard approach involves treating them with first-line antitubercular drugs to prevent the progression to active TB. Adjuvant medications are not typically used for latent TB. Close monitoring without initiating treatment can lead to the development of active TB, so immediate treatment is crucial. Screening the individual again in 10 to 12 weeks does not address the immediate need for treatment of latent TB, which is essential to prevent the progression of the disease.
2. How are antibodies produced?
- A. B cells
- B. T cells
- C. Helper cells
- D. Memory cells
Correct answer: A
Rationale: Antibodies are produced by B cells. B cells are specialized white blood cells that generate antibodies as part of the immune response. B cells differentiate into plasma cells that secrete antibodies. T cells play a role in cell-mediated immunity, not antibody production. Helper cells, or helper T cells, assist in activating B cells but do not directly produce antibodies. Memory cells store information about previous infections but do not actively produce antibodies.
3. Pain in the lower extremities due to peripheral artery disease usually worsens:
- A. with rest because blood flow increases.
- B. with elevation of the extremity because blood is diverted away.
- C. when the leg is in a dependent position because blood pools.
- D. when the leg is touched or massaged because cytokines are released.
Correct answer: B
Rationale: In peripheral artery disease, pain in the lower extremities worsens with the elevation of the extremity because it diverts blood flow away from the affected area, exacerbating the pain. Choices A, C, and D are incorrect. Resting doesn't increase blood flow, a dependent position doesn't lead to blood pooling in this context, and pain worsening due to touch or massage is not a typical feature of peripheral artery disease.
4. Which of the following steps occurs first during hemostasis?
- A. Vascular spasm
- B. Platelet plug
- C. Coagulation
- D. Dissolution of the clot
Correct answer: A
Rationale: Vascular spasm is the initial step in hemostasis, where blood vessels constrict to reduce blood flow to the injured area. This constriction helps limit blood loss until further steps like platelet plug formation and coagulation can take place. Platelet plug formation and coagulation occur after the vascular spasm, making them incorrect choices. Dissolution of the clot happens much later in the healing process, after the injury has sufficiently healed.
5. Which of the following is not an autoimmune disease?
- A. Multiple sclerosis
- B. Pernicious anemia
- C. Goodpasture syndrome
- D. Transfusion reaction
Correct answer: D
Rationale: The correct answer is D, Transfusion reaction. Transfusion reaction is not an autoimmune disease because it occurs when the immune system responds to foreign blood cells, not to the body's own cells. Choices A, B, and C (Multiple sclerosis, Pernicious anemia, Goodpasture syndrome) are autoimmune diseases where the immune system mistakenly attacks the body's own tissues or organs.
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