a staff educator is reviewing medication dosages and factors that influence medication metabolism with a group of nurses at an in service presentation
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Nursing Elites

ATI RN

ATI Pharmacology Proctored Exam 2024

1. A staff educator is reviewing medication dosages and factors that influence medication metabolism with a group of nurses at an in-service presentation. Which of the following factors should the educator include as a reason to administer lower medication dosages? (Select all that apply.)

Correct answer: C

Rationale: Liver failure impairs metabolism, leading to increased medication concentrations. When liver function is compromised, lower dosages are necessary to prevent adverse effects. Increased renal secretion is not a reason for lower medication dosages, as it primarily affects excretion rather than metabolism. Increased medication-metabolizing enzymes would usually require higher dosages to achieve the desired effect. Peripheral vascular disease does not directly impact medication metabolism or dosage requirements.

2. A client has a new prescription for Losartan. Which of the following client statements indicates an understanding of the teaching?

Correct answer: C

Rationale: The correct answer is C: 'I should monitor my blood pressure weekly.' Monitoring blood pressure regularly is crucial for clients taking Losartan, an angiotensin II receptor blocker, to ensure effective management of hypertension. This medication works to dilate blood vessels, lowering blood pressure, so monitoring is essential to assess its effectiveness. Choices A, B, and D are incorrect because increasing potassium-rich foods can be harmful due to the potassium-sparing effect of Losartan, taking the medication with milk is not recommended, and adherence to the prescribed daily dosing schedule is necessary for optimal therapeutic outcomes.

3. A client has a new prescription for Metoprolol to treat hypertension. Which of the following instructions should the nurse include?

Correct answer: C

Rationale: The correct instruction for a client taking Metoprolol, a medication used to treat hypertension, is to avoid sudden changes in position. Metoprolol can cause orthostatic hypotension, a sudden drop in blood pressure when moving from lying down to standing up, leading to dizziness and falls. By advising the client to change positions slowly, the nurse helps prevent these adverse effects and promotes safety.

4. A healthcare professional is preparing to administer verapamil by IV bolus to a client who is experiencing cardiac dysrhythmias. For which of the following adverse effects should the healthcare professional monitor when giving this medication?

Correct answer: B

Rationale: Verapamil is known to cause hypotension as one of its adverse effects due to its vasodilatory properties. Therefore, it is essential for the healthcare professional to monitor the client's blood pressure closely during and after administration to prevent complications such as severe hypotension. Hyperthermia, ototoxicity, and muscle pain are not commonly associated with verapamil administration, making choices A, C, and D incorrect.

5. A client is prescribed Clopidogrel. Which of the following laboratory values should be monitored to assess for potential adverse effects?

Correct answer: B

Rationale: Clopidogrel is an antiplatelet medication, so monitoring the client's platelet count is crucial to assess for potential bleeding complications. Changes in platelet count can indicate an increased risk of bleeding, a known adverse effect of Clopidogrel. Monitoring white blood cell count, hemoglobin, or blood glucose is not directly related to the potential adverse effects of Clopidogrel and would not provide relevant information regarding the medication's impact on platelet function.

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