ATI RN
ATI Pathophysiology Test Bank
1. A patient is receiving intravenous amphotericin. Which of the following assessments warrants the discontinuation of the antifungal agent?
- A. Sodium level of 138 mEq/L
- B. Hematocrit of 39%
- C. Blood urea nitrogen of 60 mg/dL
- D. AST level of 10 Unit/L
Correct answer: C
Rationale: Intravenous amphotericin can cause nephrotoxicity, leading to increased blood urea nitrogen levels. Elevated blood urea nitrogen (BUN) indicates impaired renal function, which is a known adverse effect of amphotericin. Therefore, a BUN level of 60 mg/dL warrants the discontinuation of the antifungal agent. The other options, such as a sodium level of 138 mEq/L, hematocrit of 39%, and AST level of 10 Unit/L, are within normal ranges and not indicative of the need to discontinue amphotericin therapy.
2. A nurse practitioner is assessing a 7-year-old boy who has been brought to the clinic by his mother, who is concerned about her son's increasingly frequent, severe headaches. Which of the nurse's questions is least likely to yield data that will confirm or rule out migraines as the cause of his problem?
- A. Does your son experience nausea or vomiting when he has a headache?
- B. Does your son have a history of recent head injury?
- C. Does your son become sensitive to light when he has a headache?
- D. Does anyone in your family have a history of migraines?
Correct answer: B
Rationale: Asking about a history of recent head injury is less likely to yield data relevant to confirming or ruling out migraines. Migraines are often associated with symptoms like nausea, vomiting, sensitivity to light, and a family history of migraines. While head injuries can cause headaches, the focus of the assessment in this case should be on symptoms more specific to migraines to guide the diagnosis and management.
3. A patient with a history of osteoporosis is prescribed raloxifene (Evista). What is the primary therapeutic effect of this medication?
- A. It stimulates the formation of new bone.
- B. It decreases bone resorption and increases bone density.
- C. It increases calcium absorption in the intestines.
- D. It increases the excretion of calcium through the kidneys.
Correct answer: B
Rationale: The correct answer is B. Raloxifene, such as Evista, works by decreasing bone resorption and increasing bone density. This medication is beneficial in the prevention and treatment of osteoporosis by slowing down the breakdown of bone tissue, thereby reducing the risk of fractures. Choices A, C, and D are incorrect because raloxifene does not directly stimulate the formation of new bone, increase calcium absorption in the intestines, or increase the excretion of calcium through the kidneys.
4. When starting on oral contraceptives, what important information should the nurse provide regarding the timing of the medication?
- A. Oral contraceptives must be taken at the same time each day to maintain consistent hormone levels and ensure effectiveness in preventing pregnancy.
- B. Oral contraceptives can be taken at any time of day as long as the schedule is consistent.
- C. Oral contraceptives should be taken with food to enhance absorption.
- D. Oral contraceptives can be skipped occasionally without significant consequences.
Correct answer: A
Rationale: When starting on oral contraceptives, it is crucial to take them at the same time each day to maintain consistent hormone levels and ensure effectiveness in preventing pregnancy. Choice B is incorrect because consistency in timing is essential for optimal efficacy. Choice C is inaccurate as oral contraceptives do not need to be taken with food for absorption. Choice D is incorrect because missing doses or skipping oral contraceptives can reduce their effectiveness in preventing pregnancy.
5. A patient with a complex medical history is considering the use of oral contraceptives. The nurse should be aware that many antibiotics and antiseizure medications cause what effect when combined with oral contraceptives?
- A. Increased risk of pregnancy
- B. Increased blood pressure
- C. Increased risk of thromboembolism
- D. Increased gastric acid
Correct answer: A
Rationale: The correct answer is A: Increased risk of pregnancy. Certain antibiotics and anticonvulsants can decrease the effectiveness of oral contraceptives by inducing liver enzymes that metabolize the hormones more quickly. This interaction can lead to a decreased contraceptive effect, thereby increasing the risk of pregnancy. Choices B, C, and D are incorrect as they do not directly relate to the effect of antibiotics and antiseizure medications on oral contraceptives.
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