ATI RN
ATI Pathophysiology Exam 1
1. A patient has been using Viagra on an intermittent basis for several years. However, he has cited delays in the onset and peak of action as the occasional source of frustration. What PDE5 inhibitor may be of particular benefit to this patient's needs?
- A. Avanafil (Stendra)
- B. Tadalafil (Cialis)
- C. Vardenafil (Levitra)
- D. Alprostadil (Caverject)
Correct answer: A
Rationale: The correct answer is Avanafil (Stendra). Avanafil has a rapid onset of action compared to other PDE5 inhibitors, making it suitable for patients experiencing delays in onset and peak of action with other medications like Viagra. Tadalafil (Cialis), Vardenafil (Levitra), and Alprostadil (Caverject) do not offer the same rapid onset of action as Avanafil, making them less suitable for addressing the specific needs of this patient.
2. An experiment is designed to determine specific cell types involved in cell-mediated immune response. The experimenter is interested in finding cells that attack cells that have specific antigens. Which cells should be isolated?
- A. Lymphokine-producing cells
- B. Cytotoxic T cells
- C. Helper T cells
- D. Macrophages
Correct answer: B
Rationale: Cytotoxic T cells are the key players in cell-mediated immunity as they directly attack cells displaying specific antigens. Lymphokine-producing cells (Choice A) are involved in cytokine production, while Helper T cells (Choice C) assist in activating other immune cells. Macrophages (Choice D) are phagocytic cells that engulf and digest pathogens, but they are not the primary cells responsible for directly attacking cells with specific antigens in cell-mediated immunity.
3. The healthcare provider is caring for a client with an altered level of consciousness and needs to assess the withdrawal reflex. Which action should the healthcare provider perform?
- A. Apply a painful stimulus to see if the client pulls away.
- B. Check for pupil response to light.
- C. Assess the client's response to verbal commands.
- D. Observe the client's reaction to a cold stimulus.
Correct answer: A
Rationale: The withdrawal reflex is assessed by applying a painful stimulus and observing if the client pulls away. This response indicates a functioning reflex arc. Choices B, C, and D are incorrect as they do not involve testing the withdrawal reflex specifically. Checking for pupil response to light assesses the pupillary reflex, assessing the client's response to verbal commands evaluates their cognitive function, and observing the client's reaction to a cold stimulus tests for a different type of sensory response.
4. What condition is a result of Polycythemia Vera, which involves excess red blood cells?
- A. Tissue ischemia & necrosis
- B. Chronic pancreatitis
- C. Low blood pressure & heart rate
- D. Increased numbers of infections
Correct answer: A
Rationale: Polycythemia Vera, characterized by excess red blood cells, can cause tissue ischemia and necrosis due to the increased blood viscosity. This condition restricts blood flow, leading to inadequate oxygen delivery to tissues and subsequent tissue damage. Choices B, C, and D are incorrect because they are not directly associated with the pathophysiology of Polycythemia Vera.
5. What serious adverse effect should the nurse monitor for during testosterone therapy?
- A. Testosterone therapy increases the risk of cardiovascular events, so regular monitoring is essential.
- B. Testosterone therapy can cause liver dysfunction, so liver function tests should be monitored regularly.
- C. Testosterone therapy can lead to prostate cancer, so regular screenings are recommended.
- D. Testosterone therapy can lead to bone fractures, so bone density should be monitored.
Correct answer: A
Rationale: The correct answer is A. Testosterone therapy is associated with an increased risk of cardiovascular events. Therefore, the nurse should monitor the patient for cardiovascular complications. While monitoring liver function tests (choice B) and bone density (choice D) may be important in some cases, the primary concern during testosterone therapy is the risk of cardiovascular events. Prostate cancer screenings (choice C) are not directly related to testosterone therapy's adverse effects.
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