ATI RN
ATI Pharmacology Test Bank
1. Why does a nurse on an oncology unit verify a client's current cumulative lifetime dose of doxorubicin before administering it to a client with breast cancer?
- A. Excessive doxorubicin can result in myelosuppression.
- B. Exceeding the lifetime cumulative dose limit of doxorubicin may lead to extravasation.
- C. An excess amount of doxorubicin can lead to cardiomyopathy.
- D. Exceeding the lifetime cumulative dose limit of doxorubicin may cause red-tinged urine and sweat.
Correct answer: C
Rationale: Verifying the client's current cumulative lifetime dose of doxorubicin is necessary because excessive amounts of the medication can lead to cardiomyopathy, a serious and potentially life-threatening side effect. By monitoring the cumulative dose, healthcare providers can help prevent cardiotoxicity and ensure patient safety during treatment.
2. What is the antidote for Heparin?
- A. Protamine sulfate
- B. Vitamin K
- C. Naloxone
- D. Toradol
Correct answer: A
Rationale: The correct answer is A: Protamine sulfate. Heparin is an anticoagulant that prevents blood clotting. Protamine sulfate is the antidote for Heparin as it binds to heparin, neutralizing its anticoagulant effects. Vitamin K is not the antidote for Heparin; it is used to reverse the effects of warfarin, another anticoagulant. Naloxone is an opioid antagonist for opioids, and Toradol is a nonsteroidal anti-inflammatory drug (NSAID) for pain relief. Therefore, the correct antidote for Heparin is Protamine sulfate.
3. When a client is starting long-term oral prednisone for chronic asthma, what adverse effect should the nurse instruct the client to monitor for?
- A. Weight gain
- B. Nervousness
- C. Bradycardia
- D. Constipation
Correct answer: A
Rationale: Weight gain is a common adverse effect of oral prednisone due to sodium and water retention, which can lead to fluid retention. Monitoring weight changes is important as it helps in early identification of this adverse effect, enabling timely interventions to manage it. Choice B, nervousness, is not typically associated with oral prednisone use. Bradycardia (Choice C) is unlikely as prednisone usually causes tachycardia or increased heart rate. Constipation (Choice D) is not a common adverse effect of prednisone compared to weight gain.
4. A client is receiving epoetin alfa to treat anemia. Which of the following findings should the nurse monitor?
- A. Leukocytosis
- B. Hypertension
- C. Hyperkalemia
- D. Fever
Correct answer: B
Rationale: The nurse should monitor the client for hypertension when receiving epoetin alfa. Epoetin alfa stimulates red blood cell production, which can lead to increased blood pressure. Monitoring blood pressure is crucial to detect and manage hypertension promptly. Leukocytosis refers to an increased white blood cell count and is not directly related to epoetin alfa treatment. Hyperkalemia is an elevated potassium level, which is not a common adverse effect of epoetin alfa. Fever is not a typical finding associated with epoetin alfa therapy.
5. A client has a new prescription for Hydrochlorothiazide. Which of the following instructions should the nurse include?
- A. Take this medication in the morning.
- B. Consume foods rich in potassium.
- C. Take this medication with a meal.
- D. Monitor for signs of dehydration.
Correct answer: D
Rationale: Hydrochlorothiazide is a diuretic that can lead to dehydration due to increased urination. Signs of dehydration include dry mouth, increased thirst, and decreased urine output. It is essential to educate the client to monitor these signs and seek medical attention if they occur. Choice A is incorrect because Hydrochlorothiazide is usually taken in the morning to prevent disruption of sleep due to increased urination during the night. Choice B is incorrect because while Hydrochlorothiazide can lead to potassium loss, consuming foods rich in potassium is not a specific instruction related to this medication. Choice C is incorrect because taking Hydrochlorothiazide with a meal is not a specific requirement for its administration.
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