ATI RN
ATI Proctored Pharmacology Test
1. When teaching a client with a prescription for Vancomycin, which instruction should the nurse include?
- A. Expect red man syndrome during treatment.
- B. Take the medication with a full glass of water.
- C. Increase your intake of potassium-rich foods.
- D. Monitor for hearing loss while taking this medication.
Correct answer: D
Rationale: The correct answer is D. Vancomycin is known to cause ototoxicity, which can result in hearing loss. Therefore, it is important for clients to monitor for any changes in their hearing while taking this medication and promptly report any issues to their healthcare provider for further evaluation and management. Choices A, B, and C are incorrect because red man syndrome is associated with rapid infusion of Vancomycin, not a common side effect during treatment; taking the medication with a full glass of water is a general instruction for many medications but not specific to Vancomycin; and increasing potassium-rich foods is not directly related to Vancomycin therapy.
2. Which drug undergoes extensive first-pass hepatic metabolism?
- A. Heparin
- B. Insulin
- C. Propranolol
- D. Nitroglycerin
Correct answer: C
Rationale: Propranolol undergoes extensive first-pass hepatic metabolism in the liver. When administered orally, propranolol is extensively metabolized by the liver before reaching systemic circulation, leading to reduced bioavailability. This process is known as first-pass hepatic metabolism, which significantly affects the drug's effectiveness and necessitates higher oral doses compared to other routes of administration. Heparin (Choice A) is not metabolized by the liver but excreted unchanged by the kidneys. Insulin (Choice B) is a peptide hormone that is not subject to significant first-pass metabolism. Nitroglycerin (Choice D) is primarily metabolized in the blood and tissues, bypassing significant first-pass metabolism in the liver.
3. When reviewing facility policies for IV therapy with the team, a nurse manager should remind the team that which technique helps minimize the risk of catheter embolism?
- A. Performing hand hygiene before and after IV insertion
- B. Rotating IV sites at least every 72 hours
- C. Minimizing tourniquet time
- D. Avoiding reinserting the needle into an IV catheter
Correct answer: D
Rationale: Avoiding reinserting the needle into an IV catheter is crucial to minimizing the risk of catheter embolism. Reinserting the needle can lead to the severing of the catheter's end, potentially causing a catheter embolism, a serious complication. The other options, while important for IV therapy safety, are not directly related to preventing catheter embolism.
4. What is the primary action of warfarin as an anticoagulant?
- A. Prevents the formation of blood clots
- B. Dissolves existing blood clots
- C. Dilates coronary arteries
- D. Treats rhythm disturbances
Correct answer: A
Rationale: The correct answer is A: "Prevents the formation of blood clots." Warfarin acts as an anticoagulant by inhibiting the synthesis of certain clotting factors in the liver. This action reduces the blood's ability to clot, making it effective in preventing the formation of blood clots. Choice B is incorrect because warfarin does not dissolve existing blood clots; it prevents their formation. Choice C is incorrect because warfarin's primary action is not to dilate coronary arteries. Choice D is incorrect as warfarin is not used to treat rhythm disturbances, but rather to prevent clot formation.
5. A client has a new prescription for Ciprofloxacin. Which of the following instructions should the nurse include?
- A. Take this medication with meals.
- B. Avoid taking this medication with dairy products.
- C. Take this medication at bedtime.
- D. Increase your intake of potassium-rich foods.
Correct answer: B
Rationale: The correct answer is B: 'Avoid taking this medication with dairy products.' Ciprofloxacin should not be taken with dairy products because calcium can interfere with the absorption of the medication. Instructing the client to take it 1 hour before or 2 hours after consuming dairy products will ensure optimal effectiveness of the medication. Choice A is incorrect because Ciprofloxacin is usually recommended to be taken on an empty stomach or with a full glass of water. Choice C is incorrect as there is no specific requirement to take Ciprofloxacin at bedtime. Choice D is also incorrect as there is no need to increase intake of potassium-rich foods in relation to taking Ciprofloxacin.
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