ATI RN
ATI Proctored Pharmacology Test
1. A client has a new prescription for a combination of oral NRTIs (abacavir, lamivudine, and zidovudine) for the treatment of HIV. Which of the following statements should the nurse include in teaching the client?
- A. These medications work by blocking HIV entry into cells.
- B. These medications work by weakening the cell wall of the HIV virus.
- C. These medications work by inhibiting enzymes to prevent HIV replication.
- D. These medications work by preventing protein synthesis within the HIV cell.
Correct answer: C
Rationale: The NRTI antiretroviral medications this client is prescribed work by inhibiting the enzyme reverse transcriptase, thus preventing HIV replication. By inhibiting this crucial enzyme, the drug interferes with the virus's ability to replicate and spread in the body. Choice A is incorrect because NRTIs do not block HIV entry into cells. Choice B is incorrect as NRTIs do not weaken the cell wall of the virus. Choice D is incorrect as NRTIs do not prevent protein synthesis within the HIV cell.
2. A client has a new prescription for alendronate to treat osteoporosis. Which of the following instructions should be included?
- A. Take the medication with food to reduce nausea.
- B. Take the medication first thing in the morning on an empty stomach.
- C. Take the medication with a full glass of milk.
- D. Take the medication with meals.
Correct answer: B
Rationale: Alendronate should be taken first thing in the morning on an empty stomach to maximize absorption. Taking it with food, milk, or meals can reduce its effectiveness by impairing absorption. Therefore, advising the client to take it on an empty stomach is crucial for optimal therapeutic outcomes.
3. A client who has a new prescription for erythromycin is receiving teaching from a healthcare provider. Which of the following statements by the client indicates an understanding of the teaching?
- A. I should take this medication with a full glass of water.
- B. I should avoid direct sunlight while taking this medication.
- C. I will take this medication on an empty stomach.
- D. I should take an antacid 30 minutes before taking this medication.
Correct answer: C
Rationale: The correct answer is C. Erythromycin should be taken on an empty stomach with a full glass of water to increase absorption. Taking it with milk (choice A) or an antacid (choice D) can interfere with its absorption. Avoiding direct sunlight (choice B) is not directly related to the administration of erythromycin.
4. What is the antidote for Warfarin?
- A. Naloxone
- B. Vitamin K
- C. Glucagon
- D. Vitamin B
Correct answer: B
Rationale: The correct antidote for Warfarin is Vitamin K. Warfarin works by inhibiting vitamin K-dependent clotting factors. Administering Vitamin K helps reverse its effects by replenishing these factors. Choices A, C, and D are incorrect. Naloxone is used to reverse opioid overdose, Glucagon is used to treat severe low blood sugar, and Vitamin B is not the antidote for Warfarin.
5. When teaching a client how to use nitroglycerin transdermal ointment for angina, which instruction should the nurse include?
- A. Remove the prior dose before applying a new dose.
- B. Rub the ointment directly into your skin until it is no longer visible.
- C. Cover the applied ointment with a clean gauze pad.
- D. Apply the ointment to the same skin area each time.
Correct answer: A
Rationale: The correct instruction is to remove the prior dose before applying a new dose. This helps prevent toxicity by ensuring the client does not inadvertently apply an excessive amount of nitroglycerin.
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