a nurse is providing discharge instructions to a client who has a new prescription for enoxaparin which of the following instructions should the nurse

ATI RN

ATI Pharmacology

1. A client is receiving discharge instructions for a new prescription of Enoxaparin. Which of the following instructions should the provider include?

A. Inject the medication into the muscle.
B. Massage the injection site after administration.
C. Rotate injection sites between the arms and thighs.
D. Administer the medication in the abdomen.

Correct answer: D

Rationale: The correct answer is to administer the medication in the abdomen. Enoxaparin is administered as a subcutaneous injection in the abdomen to prevent bleeding complications. Injecting into the muscle or massaging the site can increase the risk of bleeding. Rotating sites between the arms and thighs is not recommended for Enoxaparin administration due to variations in absorption rates. Therefore, the provider should instruct the client to administer Enoxaparin in the abdomen for optimal effectiveness and safety.

2. Which of the following is the antidote for Heparin toxicity?

A. Protamine
B. Methylene blue
C. N-acetylcysteine
D. Glucagon

Correct answer: A

Rationale: Protamine is the specific antidote for Heparin toxicity. Heparin is an anticoagulant medication, and if an overdose occurs or if there is excessive bleeding due to Heparin use, protamine, a positively charged molecule, can neutralize the anticoagulant effects of Heparin by forming a complex with it. This binding prevents Heparin from further inhibiting coagulation factors and helps in reversing its effects.

3. Which of the following is classified as a class IA Sodium Channel blocker?

A. Quinidine
B. Disopyramide
C. Aminodarone
D. Propafenone

Correct answer: A

Rationale: Quinidine is classified as a class IA sodium channel blocker. Class IA antiarrhythmics, like quinidine, work by blocking sodium channels and delaying repolarization. Propafenone, mentioned in the original rationale, is actually a class IC antiarrhythmic agent, not a class IA sodium channel blocker.

4. A client is prescribed gentamicin for an infection. Which finding indicates a potential adverse reaction to the medication?

A. Blood pressure 160/90 mm Hg
B. Presence of red blood cells in the urine
C. Urine output of 35 mL/hr
D. Respiratory rate of 22/min

Correct answer: B

Rationale: The presence of red blood cells in the urine is a significant finding that can indicate nephrotoxicity, a potential adverse effect of gentamicin. Nephrotoxicity can lead to kidney damage, and monitoring for this adverse reaction is crucial during gentamicin therapy. Elevated blood pressure (Choice A) is not typically associated with gentamicin adverse reactions. Decreased urine output (Choice C) may suggest kidney impairment but is not as specific as the presence of red blood cells in the urine. Respiratory rate (Choice D) is not directly related to potential adverse reactions to gentamicin.

5. Which of the following drugs is associated with the reaction of Cinchonism?

A. Valproic acid
B. Quinidine
C. Isoniazid
D. Ethosuximide

Correct answer: B

Rationale: Cinchonism is associated with Quinidine, not Valproic acid, Isoniazid, or Ethosuximide. Cinchonism is characterized by symptoms such as tinnitus, dizziness, and headaches. Quinidine, being an antiarrhythmic agent, can lead to this condition as a side effect.