ATI RN
Proctored Pharmacology ATI
1. A client receiving chemotherapy with Methotrexate asks why Leucovorin is being given. Which of the following responses should the nurse use?
- A. Leucovorin reduces the risk of a transfusion reaction from Methotrexate.
- B. Leucovorin increases platelet production and prevents bleeding.
- C. Leucovorin potentiates the cytotoxic effects of Methotrexate.
- D. Leucovorin protects healthy cells from Methotrexate's toxic effects.
Correct answer: D
Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment. Choices A, B, and C are incorrect because Leucovorin does not reduce the risk of a transfusion reaction from Methotrexate, increase platelet production, prevent bleeding, or potentiate the cytotoxic effects of Methotrexate. Instead, Leucovorin works by rescuing healthy cells from the toxic effects of Methotrexate.
2. A client reports using over-the-counter calcium carbonate antacid. Which of the following recommendations should the nurse make about taking this medication?
- A. Decrease bulk in the diet to counteract the adverse effect of diarrhea.
- B. Take the medication with dairy products to increase absorption.
- C. Reduce sodium intake.
- D. Drink a glass of water after taking the medication.
Correct answer: D
Rationale: The correct recommendation for taking calcium carbonate antacid is to drink a glass of water after taking the medication. This practice enhances the effectiveness of the antacid by promoting its dissolution and absorption in the stomach, providing relief from symptoms of heartburn and indigestion. Choices A, B, and C are incorrect. Choice A is not relevant as calcium carbonate antacid does not typically cause diarrhea. Choice B is inaccurate as taking calcium carbonate with dairy products may decrease its absorption due to the presence of calcium in both sources. Choice C is unrelated to the administration of calcium carbonate antacid.
3. A client is prescribed Ranitidine. Which of the following laboratory results should be monitored by the nurse?
- A. Complete blood count (CBC).
- B. Serum creatinine.
- C. Serum potassium.
- D. Serum glucose.
Correct answer: A
Rationale: Ranitidine can potentially lead to blood dyscrasias, necessitating the monitoring of the client's CBC. Checking the CBC can help detect any abnormalities in blood cell counts and assess the client's overall hematologic status during Ranitidine therapy.
4. A client is taking Amiodarone to treat Atrial Fibrillation. Which of the following findings is a manifestation of Amiodarone toxicity?
- A. Light yellow urine
- B. Report of tinnitus
- C. Productive cough
- D. Blue-gray skin discoloration
Correct answer: D
Rationale: Blue-gray skin discoloration is a common sign of Amiodarone toxicity, known as blue-gray discoloration, which can affect areas like the face, neck, or hands. It is important to monitor for this side effect, as it can be a visible indicator of potential toxicity. Choices A, B, and C are incorrect. Light yellow urine is not typically associated with Amiodarone toxicity. Tinnitus is not a common manifestation of Amiodarone toxicity. A productive cough is not a recognized symptom of Amiodarone toxicity.
5. A client has a prescription for Trimethoprim-Sulfamethoxazole. Which of the following instructions should the nurse include?
- A. Take the medication with food.
- B. Increase fluid intake.
- C. Expect reddish-orange urine.
- D. Avoid high-protein foods.
Correct answer: B
Rationale: The correct instruction for a client prescribed Trimethoprim-Sulfamethoxazole is to increase fluid intake. This helps prevent crystalluria and kidney stones, which are potential adverse effects of this medication. Adequate hydration is essential to reduce the risk of these complications.
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