ATI RN
ATI Pharmacology Test Bank
1. A healthcare professional is caring for a group of clients receiving antimicrobial therapy. Which of the following clients should the professional plan to monitor for manifestations of antibiotic toxicity?
- A. An adolescent client with a sinus infection
- B. An older adult client with prostatitis
- C. A client who is postpartum with mastitis
- D. A middle-aged client with a urinary tract infection
Correct answer: B
Rationale: An older adult client with prostatitis who is receiving antibiotics should be monitored for toxicity due to age-related reductions in medication metabolism and excretion. Older adults are more susceptible to antibiotic toxicity, making them a high-risk group for adverse effects.
2. What finding should a nurse monitor for as an adverse effect when a client has a new prescription for Spironolactone?
- A. Hyperkalemia
- B. Hypoglycemia
- C. Hypocalcemia
- D. Hyponatremia
Correct answer: A
Rationale: The correct answer is hyperkalemia. Spironolactone is a potassium-sparing diuretic that can lead to an increase in potassium levels. Hyperkalemia can be dangerous, causing muscle weakness and cardiac dysrhythmias. Monitoring potassium levels closely is crucial when a client is on Spironolactone. Hypoglycemia (choice B) is incorrect because Spironolactone does not typically affect blood glucose levels. Hypocalcemia (choice C) and hyponatremia (choice D) are also incorrect as Spironolactone's primary impact is on potassium levels.
3. A client has a new prescription for Phenytoin. Which of the following instructions should the nurse include?
- A. Brush and floss your teeth regularly.
- B. Avoid drinking grapefruit juice.
- C. Take this medication with food.
- D. Increase your intake of calcium-rich foods.
Correct answer: A
Rationale: The correct answer is to instruct the client to brush and floss their teeth regularly. Phenytoin can lead to gingival hyperplasia, making oral hygiene crucial to prevent complications. Encouraging good oral care practices helps reduce the risk of adverse effects on the gums and teeth. Avoiding grapefruit juice is not specifically related to Phenytoin. While some medications require intake with food, Phenytoin is usually taken on an empty stomach for better absorption. Increasing calcium-rich foods is not directly associated with Phenytoin therapy.
4. What are the Therapeutic Effects of Lithium?
- A. Prevents or decreases the incidence of acute manic episodes
- B. Maintenance of blood glucose
- C. Control of hyperglycemia in diabetic patients
- D. Diminished seizure activity
Correct answer: A
Rationale: The therapeutic effect of lithium is that it prevents or decreases the incidence of acute manic episodes in patients with bipolar disorder. Lithium is commonly used as a mood stabilizer in the treatment of bipolar disorder due to its ability to reduce the frequency and severity of manic episodes. Choices B, C, and D are incorrect as lithium is not used for the maintenance of blood glucose, control of hyperglycemia in diabetic patients, or to diminish seizure activity. These effects are not associated with the use of lithium as a medication.
5. A healthcare professional is educating a client who is starting therapy with gemcitabine. Which of the following findings should the healthcare professional instruct the client to report?
- A. Dyspnea
- B. Constipation
- C. Tinnitus
- D. Dry mouth
Correct answer: A
Rationale: The healthcare professional should instruct the client to report dyspnea since it can indicate pulmonary toxicity, a severe adverse effect associated with gemcitabine therapy. Monitoring and reporting dyspnea promptly can help in early detection and management of potential serious complications. Constipation, tinnitus, and dry mouth are not typically associated with gemcitabine therapy and are not urgent findings requiring immediate reporting.
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