a nurse is caring for a group of clients who are receiving antimicrobial therapy which of the following clients should the nurse plan to monitor for m

ATI RN

ATI Pharmacology Test Bank

1. A healthcare professional is caring for a group of clients receiving antimicrobial therapy. Which of the following clients should the professional plan to monitor for manifestations of antibiotic toxicity?

A. An adolescent client with a sinus infection
B. An older adult client with prostatitis
C. A client who is postpartum with mastitis
D. A middle-aged client with a urinary tract infection

Correct answer: B

Rationale: An older adult client with prostatitis who is receiving antibiotics should be monitored for toxicity due to age-related reductions in medication metabolism and excretion. Older adults are more susceptible to antibiotic toxicity, making them a high-risk group for adverse effects.

2. Which of the following is commonly used to treat migraine headaches?

A. Beta-blockers
B. Cholinesterase Inhibitors
C. ACE inhibitors
D. Anti-epileptic drugs (AEDs)

Correct answer: D

Rationale: Anti-epileptic drugs (AEDs) are often used in the management of migraine headaches due to their ability to help prevent or reduce the frequency and intensity of migraines. They work by stabilizing electrical activity in the brain, which can help in controlling migraine symptoms. While beta-blockers are also sometimes used in migraine prevention, anti-epileptic drugs are more commonly associated with migraine treatment. Cholinesterase Inhibitors are not typically used for migraine headaches, as they are more commonly associated with conditions like Alzheimer's disease. ACE inhibitors are a type of medication used to treat conditions like high blood pressure and heart failure, but they are not a first-line treatment for migraines.

3. While providing an Angiotensin-converting enzyme (ACE) inhibitor, the patient asks what the action of the drug is. As a healthcare provider, you explain that the action of an ACE inhibitor is:

A. To lower blood pressure by blocking the conversion of angiotensin I to vasoconstrictor angiotensin II
B. To inhibit reabsorption of sodium back into the body, ultimately increasing urine output and lowering blood pressure
C. To decrease heart rate and blood pressure by competing with Beta1 and Beta2 receptors in the heart and lungs
D. To lower blood glucose by stimulating the release of insulin

Correct answer: A

Rationale: ACE inhibitors lower blood pressure by blocking the conversion of angiotensin I to vasoconstrictor angiotensin II. Angiotensin II is a potent vasoconstrictor, and by inhibiting its formation, ACE inhibitors help dilate blood vessels, reduce blood pressure, and decrease the workload on the heart. Choice B is incorrect as it describes the mechanism of action of diuretics, not ACE inhibitors. Choice C is incorrect as it refers to the action of beta-blockers, not ACE inhibitors. Choice D is incorrect as it describes the mechanism of action of antidiabetic medications, not ACE inhibitors.

4. Which statement is true about food and drug precautions?

A. Limiting certain types of food or administering certain types of drugs is necessary.
B. Certain combinations of food and drugs can cause adverse reactions.
C. Precautions may involve limiting certain types of food or administering drugs rather than restricting the drug itself.
D. When one drug alters the way another drug affects the body.

Correct answer: B

Rationale: The correct answer is B. Certain combinations of food and drugs can indeed lead to adverse reactions. It is important to be cautious with the simultaneous intake of food and drugs as interactions between them can affect their efficacy and safety. Choices A, C, and D are incorrect because they do not accurately reflect the potential risks associated with the combination of food and drugs.

5. What is the antidote for Warfarin?

A. Vitamin D
B. Vitamin C
C. Vitamin K
D. Vitamin B6

Correct answer: C

Rationale: Vitamin K is the antidote for Warfarin toxicity as it helps reverse the anticoagulant effects of Warfarin. Warfarin works by inhibiting vitamin K-dependent clotting factors, and administering vitamin K can replenish these factors, thereby counteracting the anticoagulant effects of Warfarin. Vitamin D, Vitamin C, and Vitamin B6 do not have the specific mechanism to counteract the anticoagulant effects of Warfarin, making them incorrect choices.