ATI RN
ATI Pharmacology Test Bank
1. A client has a new prescription for Enfuvirtide to treat HIV infection. The nurse should monitor the client for which of the following adverse reactions?
- A. Bone marrow suppression
- B. Pancreatitis
- C. Pancreatitis
- D. Bone marrow suppression
Correct answer: D
Rationale: While bone marrow suppression is not typically associated with Enfuvirtide, a more relevant concern is the risk of severe allergic reactions such as anaphylaxis. Enfuvirtide, an HIV fusion inhibitor, can cause local injection site reactions and systemic allergic responses. Monitoring for signs of allergic reactions, such as rash, fever, and difficulty breathing, is crucial to ensure the client's safety.
2. While caring for a client receiving Heparin therapy, which of the following laboratory tests should the nurse monitor to evaluate the effectiveness of the therapy?
- A. PT
- B. INR
- C. aPTT
- D. Platelet count
Correct answer: C
Rationale: The nurse should monitor the aPTT (activated partial thromboplastin time) when caring for a client receiving Heparin therapy. The aPTT reflects the intrinsic pathway of the clotting cascade and is used to monitor the effectiveness of heparin, which primarily affects this pathway by potentiating antithrombin III. Monitoring the aPTT helps ensure that the client's blood is within the therapeutic range to prevent thrombus formation. Choices A, B, and D are incorrect. PT (Prothrombin Time) and INR (International Normalized Ratio) are used to monitor Warfarin therapy, not Heparin. Platelet count is important in assessing for thrombocytopenia but is not a specific indicator of Heparin therapy effectiveness.
3. A healthcare professional is administering a Dopamine infusion at a low dose to a client with severe heart failure. Which of the following findings is an expected effect of this medication?
- A. Lowered heart rate
- B. Increased myocardial contractility
- C. Decreased conduction through the AV node
- D. Vasoconstriction of renal blood vessels
Correct answer: B
Rationale: Dopamine, when administered at a low dose, is expected to increase myocardial contractility by stimulating beta1 receptors. This positive inotropic effect leads to an increase in cardiac output. Therefore, the correct answer is increased myocardial contractility, as it is a desired effect of administering dopamine to a client with severe heart failure.
4. A healthcare professional is preparing a client's medications. Which of the following actions should the professional take to follow legal practice guidelines? (Select all that apply.)
- A. Maintain skill competency.
- B. Determine the dosage.
- C. Monitor for adverse effects.
- D. Safeguard medications.
Correct answer: A
Rationale: Maintaining skill competency is a critical aspect of legal practice guidelines for healthcare professionals. It is essential to ensure that healthcare professionals are competent and up-to-date with their skills to provide safe and effective care to patients. While determining the dosage, monitoring for adverse effects, and safeguarding medications are important aspects of medication administration, maintaining skill competency is a fundamental legal responsibility that ensures the delivery of quality care. Determining the dosage and monitoring for adverse effects are clinical responsibilities, while safeguarding medications pertains to proper storage and handling, not specifically related to legal practice guidelines.
5. When teaching a client how to use nitroglycerin transdermal ointment for angina, which instruction should the nurse include?
- A. Remove the prior dose before applying a new dose.
- B. Rub the ointment directly into your skin until it is no longer visible.
- C. Cover the applied ointment with a clean gauze pad.
- D. Apply the ointment to the same skin area each time.
Correct answer: A
Rationale: The correct instruction is to remove the prior dose before applying a new dose. This helps prevent toxicity by ensuring the client does not inadvertently apply an excessive amount of nitroglycerin.
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