ATI RN
ATI Pharmacology Test Bank
1. A client has a new prescription for Enfuvirtide to treat HIV infection. The nurse should monitor the client for which of the following adverse reactions?
- A. Bone marrow suppression
- B. Pancreatitis
- C. Pancreatitis
- D. Bone marrow suppression
Correct answer: D
Rationale: While bone marrow suppression is not typically associated with Enfuvirtide, a more relevant concern is the risk of severe allergic reactions such as anaphylaxis. Enfuvirtide, an HIV fusion inhibitor, can cause local injection site reactions and systemic allergic responses. Monitoring for signs of allergic reactions, such as rash, fever, and difficulty breathing, is crucial to ensure the client's safety.
2. A client reports using over-the-counter calcium carbonate antacid. Which of the following recommendations should the nurse make about taking this medication?
- A. Decrease bulk in the diet to counteract the adverse effect of diarrhea.
- B. Take the medication with dairy products to increase absorption.
- C. Reduce sodium intake.
- D. Drink a glass of water after taking the medication.
Correct answer: D
Rationale: The correct recommendation for taking calcium carbonate antacid is to drink a glass of water after taking the medication. This practice enhances the effectiveness of the antacid by promoting its dissolution and absorption in the stomach, providing relief from symptoms of heartburn and indigestion. Choices A, B, and C are incorrect. Choice A is not relevant as calcium carbonate antacid does not typically cause diarrhea. Choice B is inaccurate as taking calcium carbonate with dairy products may decrease its absorption due to the presence of calcium in both sources. Choice C is unrelated to the administration of calcium carbonate antacid.
3. When should a blood sample be obtained for a peak serum level of gentamicin when administered by IV infusion for 1 hour at 0900?
- A. 1000
- B. 1030
- C. 1100
- D. 1130
Correct answer: B
Rationale: The nurse should obtain the blood sample for the peak serum level at 1030. This timing allows for 30 minutes to elapse after the completion of the 1-hour IV infusion, which is the recommended window for obtaining the peak serum level of gentamicin.
4. A client has a new prescription for Filgrastim. Which of the following instructions should be included by the healthcare provider?
- A. Take this medication with food.
- B. Avoid taking this medication with orange juice.
- C. Report bone pain to your healthcare provider.
- D. Expect a persistent cough while taking this medication.
Correct answer: C
Rationale: The correct answer is C: 'Report bone pain to your healthcare provider.' Filgrastim is known to cause bone pain as a common side effect. Therefore, it is crucial for clients to report any bone pain to their healthcare provider to monitor for potential complications or the need for further management. Choices A, B, and D are incorrect because taking Filgrastim with food, avoiding it with orange juice, and expecting a persistent cough are not relevant instructions associated with this medication.
5. A client is taking metformin for type 2 diabetes. Which of the following findings should indicate to the nurse that the medication is effective?
- A. Increased urine output
- B. Decreased fasting blood glucose
- C. Decreased hemoglobin A1C
- D. Decreased polyuria
Correct answer: C
Rationale: A decrease in hemoglobin A1C is a more specific indicator of metformin's effectiveness in controlling blood glucose levels over a longer period compared to fasting blood glucose levels. Hemoglobin A1C reflects average blood sugar levels over the past 2-3 months, providing a more comprehensive view of glycemic control. Increased urine output (choice A) is not a direct indicator of metformin's effectiveness and can be influenced by various factors. Decreased fasting blood glucose (choice B) can fluctuate due to various reasons and may not provide a reliable long-term assessment of metformin's efficacy. Decreased polyuria (choice D) refers to a symptom rather than a direct measure of metformin's effectiveness in managing diabetes.
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