a nurse is caring for a client who has a new prescription for enfuvirtide to treat hiv infection the nurse should monitor the client for which of the

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ATI Pharmacology Test Bank

1. A client has a new prescription for Enfuvirtide to treat HIV infection. The nurse should monitor the client for which of the following adverse reactions?

A. Bone marrow suppression
B. Pancreatitis
C. Pancreatitis
D. Bone marrow suppression

Correct answer: D

Rationale: While bone marrow suppression is not typically associated with Enfuvirtide, a more relevant concern is the risk of severe allergic reactions such as anaphylaxis. Enfuvirtide, an HIV fusion inhibitor, can cause local injection site reactions and systemic allergic responses. Monitoring for signs of allergic reactions, such as rash, fever, and difficulty breathing, is crucial to ensure the client's safety.

2. A healthcare professional is preparing to administer Spironolactone to a client. Which of the following laboratory results should the professional review before administering this medication?

A. Serum potassium.
B. Serum sodium.
C. Serum chloride.
D. Serum calcium.

Correct answer: A

Rationale: When administering Spironolactone, it is essential to monitor the client's serum potassium levels because Spironolactone is a potassium-sparing diuretic. Monitoring potassium levels helps to detect hyperkalemia, a potential adverse effect of the medication.

3. The healthcare professional is preparing to administer atenolol (Tenormin) to a client with angina. Which vital sign would cause the healthcare professional to question administering this drug?

A. Respirations 12 breaths per minute
B. Pulse 52 beats per minute
C. Blood pressure 134/72
D. Oxygen saturation 95%

Correct answer: B

Rationale: Atenolol is a beta-blocker medication that can lower heart rate. A pulse of 52 beats per minute is relatively low and administering atenolol could further decrease the heart rate, potentially leading to bradycardia. Monitoring the pulse rate and holding the medication if the pulse is below the prescribed parameters is crucial to prevent adverse effects such as bradycardia and hypotension.

4. What is the correct definition of drug absorption?

A. Movement of a drug from the site of administration to various tissues of the body
B. Describes the absorption, distribution, metabolism, and excretion of drugs
C. These types of drugs can be taken over the counter
D. This addresses how various drugs affect different forms of the body

Correct answer: A

Rationale: The correct definition of drug absorption is the movement of a drug from the site of administration into various tissues of the body. It is the process by which a drug is taken up and enters the systemic circulation. Choice B describes the pharmacokinetics of drugs, including absorption, distribution, metabolism, and excretion, but it is not a specific definition of drug absorption. Choice C is unrelated to drug absorption, as it refers to over-the-counter drugs. Choice D is too vague and does not specifically address the process of drug absorption.

5. Which of the following is the antidote for Heparin toxicity?

A. Protamine
B. Methylene blue
C. N-acetylcysteine
D. Glucagon

Correct answer: A

Rationale: Protamine is the specific antidote for Heparin toxicity. Heparin is an anticoagulant medication, and if an overdose occurs or if there is excessive bleeding due to Heparin use, protamine, a positively charged molecule, can neutralize the anticoagulant effects of Heparin by forming a complex with it. This binding prevents Heparin from further inhibiting coagulation factors and helps in reversing its effects.