ATI RN
ATI Proctored Pharmacology Test
1. A healthcare professional in a provider's clinic is caring for a client who reports erectile dysfunction and requests a prescription for sildenafil. Which of the following medications currently prescribed for the client is a contraindication to taking sildenafil?
- A. Isosorbide
- B. Phenytoin
- C. Metronidazole
- D. Prednisone
Correct answer: A
Rationale: Sildenafil is contraindicated with nitrates like isosorbide due to the risk of severe hypotension. Isosorbide is a nitrate that can potentiate the hypotensive effects of sildenafil, leading to a dangerous drop in blood pressure. Therefore, it is essential to avoid concurrent use of isosorbide and sildenafil to prevent adverse effects. Phenytoin, metronidazole, and prednisone do not have significant interactions with sildenafil and are not contraindicated when used together.
2. A client has a new prescription for Trimethoprim-sulfamethoxazole. Which of the following information should the nurse include?
- A. Take the medication on an empty stomach.
- B. Maintain a fluid restriction while taking it.
- C. Take it with food.
- D. Stop taking it when manifestations subside.
Correct answer: C
Rationale: The correct answer is C: 'Take it with food.' Trimethoprim-sulfamethoxazole can cause gastrointestinal upset, and taking it with food helps reduce the risk of stomach irritation. It should not be taken on an empty stomach. Maintaining good hydration is important to prevent kidney-related side effects, so maintaining a fluid restriction, as in choice B, is not appropriate. Additionally, stopping the medication when manifestations subside, as in choice D, is incorrect as antibiotics should be taken for the full prescribed course to ensure eradication of the infection and to prevent antibiotic resistance.
3. When administering an Antiulcer Agent, you should be more cautious when administering it to:
- A. A healthy 27-year-old patient
- B. Patient with renal failure
- C. Elderly patients
- D. Choices B & C
Correct answer: D
Rationale: When administering an antiulcer agent, caution is warranted in patients with renal failure due to the potential impact on drug metabolism and excretion. Additionally, elderly patients may be more susceptible to adverse effects from antiulcer agents due to age-related physiological changes. Therefore, it is important to be more cautious when administering antiulcer agents to patients with renal failure and elderly patients. Choice A, a healthy 27-year-old patient, would typically not require as much caution compared to patients with renal failure or elderly patients when administering antiulcer agents. Therefore, choices B & C are the correct options for increased caution.
4. A client has a new prescription for Fluoxetine for PTS. Which of the following statements should the nurse include in the teaching?
- A. You may have a decreased desire for intimacy while taking this medication.
- B. You should take this medication at bedtime to help promote sleep.
- C. You will have fewer urinary adverse effects if you urinate just before taking this medication.
- D. You'll need to wear sunglasses when outdoors due to the light sensitivity caused by this medication.
Correct answer: A
Rationale: The correct statement for the nurse to include in the teaching is 'You may have a decreased desire for intimacy while taking this medication.' One of the potential adverse effects of fluoxetine and other SSRIs is a decreased desire for intimacy. It is essential for the nurse to educate the client about this possible side effect to enhance understanding and promote informed decision-making. Choices B, C, and D are incorrect because they do not relate to common side effects of Fluoxetine that the nurse should include in the teaching.
5. A client has a new prescription for transdermal patches. Which statement should the client make to indicate understanding of the instructions?
- A. I will clean the site with an alcohol swab before applying the patch.
- B. I will rotate the application sites weekly.
- C. I will apply the patch to an area of skin with no hair.
- D. I will place the new patch on the site of the old patch.
Correct answer: C
Rationale: The correct answer is C. Applying the patch to a hairless area of skin is essential for optimal medication absorption. Hair can interfere with the patch's adherence and effectiveness. It is important for the client to choose a site without hair to ensure proper delivery of the medication. Choices A, B, and D are incorrect because cleaning the site with an alcohol swab (Choice A) is a good practice but not the most crucial aspect for transdermal patch application. Rotating application sites weekly (Choice B) is more relevant for injections to prevent skin irritation or breakdown. Placing the new patch on the site of the old patch (Choice D) can lead to skin irritation and poor absorption due to a build-up of medication.
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