ATI RN
ATI Pharmacology Proctored Exam 2023
1. A healthcare professional is preparing to administer heparin 15,000 units subcutaneously every 12 hours. The available heparin injection is 20,000 units/mL. How many milliliters should the healthcare professional administer per dose?
- A. 0.8 mL
- B. 0.75 mL
- C. 0.5 mL
- D. 1 mL
Correct answer: A
Rationale: To calculate the volume to administer, use the formula: Desired dose / Concentration = Volume to administer. In this case, (15,000 units / 20,000 units/mL) = 0.75 mL. Since the volume needs to be rounded up to the nearest tenth, the correct answer is 0.8 mL. Choice B (0.75 mL) is incorrect because it does not account for rounding up the volume. Choices C (0.5 mL) and D (1 mL) are incorrect as they do not reflect the precise calculation based on the given concentration and desired dose.
2. A client is to receive Pamidronate for bone pain related to cancer. What precaution should the nurse take during the administration of Pamidronate?
- A. Inspect the skin for redness and irritation around the injection site.
- B. Assess the IV site for thrombophlebitis frequently during administration.
- C. Instruct the client to lie down for 30 minutes after oral administration.
- D. Monitor for signs of anaphylaxis for 20 minutes after intramuscular injection.
Correct answer: B
Rationale: Pamidronate is typically administered through IV infusion, which can cause irritation to veins. The nurse should frequently assess the IV site for thrombophlebitis during the administration to promptly detect any potential complications related to the infusion. Inspecting the skin for redness and irritation around the injection site (Choice A) is not directly related to IV infusion. Instructing the client to lie down after oral administration (Choice C) is not necessary for IV administration. Monitoring for signs of anaphylaxis after an intramuscular injection (Choice D) is not relevant for an IV infusion of Pamidronate.
3. What is a serious adverse reaction to penicillin?
- A. Liver Failure
- B. Anaphylaxis
- C. Respiratory Depression
- D. Edema
Correct answer: B
Rationale: The correct answer is B: Anaphylaxis. Anaphylaxis is a severe allergic reaction that can occur as a serious adverse reaction to penicillin. It is a life-threatening condition that requires immediate medical attention. Choices A, C, and D are incorrect. Liver failure is not a typical adverse reaction to penicillin, respiratory depression is more commonly associated with opioid medications, and edema is not a common severe adverse reaction to penicillin.
4. When preparing to administer IV Acyclovir for Herpes Zoster, what action should the nurse take?
- A. Infuse the medication over 1 hour.
- B. Monitor the client's blood pressure every 15 minutes during infusion.
- C. Administer a stool softener.
- D. Monitor the client's blood glucose level every 4 hours during infusion.
Correct answer: A
Rationale: The correct action for the nurse is to infuse IV Acyclovir over at least 1 hour to prevent nephrotoxicity. Rapid infusion can lead to adverse effects, so a slow infusion rate is crucial for patient safety. Monitoring blood pressure, administering a stool softener, or monitoring blood glucose levels are not directly related to the administration of IV Acyclovir for Herpes Zoster.
5. A client has a new prescription for Verapamil. Which of the following instructions should the nurse include?
- A. Take this medication at bedtime.
- B. Monitor for signs of hyperglycemia.
- C. Avoid drinking grapefruit juice.
- D. Increase your intake of potassium-rich foods.
Correct answer: C
Rationale: The correct answer is to instruct the client to avoid drinking grapefruit juice. Grapefruit juice can inhibit the metabolism of Verapamil, leading to increased blood levels of the medication, which can potentiate its effects, potentially causing adverse reactions like hypotension and bradycardia. Choices A, B, and D are incorrect. Taking Verapamil at bedtime is not a specific instruction related to its metabolism or side effects. Monitoring for signs of hyperglycemia is not directly related to Verapamil use. Increasing potassium-rich foods intake is not necessary with Verapamil and could potentially lead to hyperkalemia in some cases.
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