ATI RN
ATI Pharmacology Proctored Exam 2023
1. A client is receiving IV Dopamine for the treatment of shock. Which of the following findings indicates that the medication is effective?
- A. Increased heart rate
- B. Decreased blood pressure
- C. Increased urine output
- D. Decreased respiratory rate
Correct answer: C
Rationale: The correct answer is increased urine output. Dopamine increases cardiac output and improves renal perfusion, leading to increased urine output. This response indicates that the medication is effective in treating shock by enhancing renal function and perfusion. Choices A, B, and D are incorrect because an increased heart rate, decreased blood pressure, and decreased respiratory rate are not findings that indicate the effectiveness of IV Dopamine in treating shock.
2. A client has a new prescription for Hydrochlorothiazide. Which of the following information should the nurse include?
- A. Take the medication with food.
- B. Plan to take the medication at bedtime.
- C. Expect increased swelling of the ankles.
- D. Limit fluid intake in the morning.
Correct answer: A
Rationale: When educating a client about taking Hydrochlorothiazide, the nurse should advise taking the medication with food or after meals to prevent gastrointestinal upset. This medication is a diuretic, so it is important to maintain adequate fluid intake throughout the day to prevent dehydration. Taking it at bedtime is not necessary, and increased swelling of the ankles is not an expected side effect of this medication. Limiting fluid intake in the morning is not necessary and could lead to dehydration, which is a potential side effect of this diuretic.
3. A client asks the nurse how Rituximab works, which the client is receiving to treat Non-Hodgkin's Leukemia. Which of the following should the nurse include?
- A. Blocks hormone receptors
- B. Increases immune response
- C. Binds with specific antigens on tumor cells
- D. Stops DNA replication during cell division
Correct answer: C
Rationale: Rituximab is a monoclonal antibody that binds with specific antigens on B-lymphocytes, leading to the destruction of cancer cells. In the context of Non-Hodgkin's Leukemia, Rituximab targets and destroys cancerous B-lymphocytes, which helps in treating the disease. Choices A, B, and D are incorrect. Rituximab does not block hormone receptors, increase immune response, or stop DNA replication during cell division. The primary mode of action of Rituximab is its binding with specific antigens on tumor cells, specifically B-lymphocytes, to elicit an immune response against cancerous cells.
4. What should you monitor when administering Clopidogrel to a patient?
- A. Signs of thrombotic thrombocytopenic purpura
- B. Bleeding during therapy
- C. CBC with differential and platelet count
- D. All of the above
Correct answer: D
Rationale: When administering Clopidogrel, it is crucial to monitor for signs of thrombotic thrombocytopenic purpura, bleeding during therapy, and changes in CBC with differential and platelet count. Thrombotic thrombocytopenic purpura is a rare but serious condition associated with Clopidogrel use, characterized by microangiopathic hemolytic anemia, thrombocytopenia, neurological symptoms, fever, and renal dysfunction. Monitoring for signs of thrombotic thrombocytopenic purpura is essential to detect this potentially life-threatening condition early. Monitoring for bleeding helps to assess the risk of hemorrhagic events, a known side effect of Clopidogrel. Additionally, regular monitoring of CBC with differential and platelet count is necessary to evaluate the drug's impact on blood cell counts and detect any abnormalities that may require intervention. Therefore, monitoring all these parameters is vital to ensure patient safety and appropriate management during Clopidogrel therapy.
5. A client has a new prescription for Nitroglycerin sublingual tablets. Which of the following instructions should the nurse include?
- A. Take one tablet every 15 minutes until pain is relieved.
- B. Take one tablet every 5 minutes, up to three doses.
- C. Take one tablet at bedtime.
- D. Take one tablet on an empty stomach.
Correct answer: B
Rationale: The correct administration of Nitroglycerin sublingual tablets involves taking one tablet at the onset of chest pain and repeating every 5 minutes for up to three doses. This protocol helps in managing angina episodes effectively. Choice A suggests taking a tablet every 15 minutes until pain relief, which may delay appropriate intervention. Choice C, taking a tablet at bedtime, is not suitable for immediate relief during angina attacks. Choice D, taking a tablet on an empty stomach, is unrelated to the correct administration of Nitroglycerin sublingual tablets.
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