which of the following is the primary site of activity for the drug warfarin
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Nursing Elites

ATI RN

ATI Pharmacology Proctored

1. Which of the following is the primary site of activity for the drug Warfarin?

Correct answer: B

Rationale: Warfarin primarily affects the liver where it inhibits the synthesis of clotting factors.

2. A client has a new prescription for Lovastatin. Which of the following instructions should be included?

Correct answer: C

Rationale: Lovastatin should be taken at bedtime because cholesterol production in the liver is highest at night, making the medication more effective in reducing cholesterol levels. By taking it at bedtime, the medication aligns with the body's natural rhythm of cholesterol synthesis, optimizing its therapeutic effects.

3. In the management of nausea due to gastroparesis in a client with Diabetes, which of the following medications may be prescribed?

Correct answer: B

Rationale: Metoclopramide, as a dopamine antagonist, is commonly prescribed to manage nausea and improve gastric motility in clients with diabetic gastroparesis. By enhancing gastric emptying, it can help alleviate symptoms like bloating and nausea associated with gastroparesis. Choice A, Lubiprostone, is primarily used to treat chronic idiopathic constipation and irritable bowel syndrome with constipation, not nausea due to gastroparesis. Choice C, Bisacodyl, is a stimulant laxative used for the treatment of constipation and bowel preparation before procedures, not for nausea associated with gastroparesis. Choice D, Loperamide, is an antimotility agent used to manage diarrhea, not nausea or gastric motility issues seen in gastroparesis.

4. When should a blood sample be obtained for a peak serum level of gentamicin when administered by IV infusion for 1 hour at 0900?

Correct answer: B

Rationale: The nurse should obtain the blood sample for the peak serum level at 1030. This timing allows for 30 minutes to elapse after the completion of the 1-hour IV infusion, which is the recommended window for obtaining the peak serum level of gentamicin.

5. When educating a client who has a prescription for Propranolol, what instruction should the healthcare provider include?

Correct answer: D

Rationale: The correct instruction for a client with a prescription for Propranolol is not to stop taking the medication abruptly. Abrupt cessation can result in rebound hypertension or other cardiac complications. It is crucial for the client to taper off the medication gradually under healthcare provider supervision to prevent adverse effects. Choice A is incorrect because Propranolol can be taken with or without food. Choice B is incorrect as discontinuing the medication based on fatigue alone is not advisable without consulting a healthcare provider. Choice C is incorrect because while Propranolol can decrease heart rate, it is not the primary instruction to provide in this scenario.

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