which of the following is the primary site of activity for the drug warfarin
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Nursing Elites

ATI RN

ATI Pharmacology Proctored

1. Which of the following is the primary site of activity for the drug Warfarin?

Correct answer: B

Rationale: Warfarin primarily affects the liver where it inhibits the synthesis of clotting factors.

2. What is the antidote for Warfarin?

Correct answer: C

Rationale: Vitamin K is the antidote for Warfarin toxicity as it helps reverse the anticoagulant effects of Warfarin. Warfarin works by inhibiting vitamin K-dependent clotting factors, and administering vitamin K can replenish these factors, thereby counteracting the anticoagulant effects of Warfarin. Vitamin D, Vitamin C, and Vitamin B6 do not have the specific mechanism to counteract the anticoagulant effects of Warfarin, making them incorrect choices.

3. A client has a prescription for Nitroglycerin, and a nurse is providing teaching. Which of the following instructions should the nurse include?

Correct answer: B

Rationale: The correct instruction for taking Nitroglycerin is to take one tablet at the onset of chest pain, then repeat every 5 minutes for up to three doses. Option A is incorrect because taking a tablet every 15 minutes until pain is relieved may lead to delayed intervention. Option C is incorrect as taking Nitroglycerin at bedtime is not indicated for chest pain. Option D is incorrect as Nitroglycerin should be taken sublingually at the onset of chest pain, not on an empty stomach.

4. Which of the following is considered a class IA Sodium Channel blocker?

Correct answer: D

Rationale: Procainamide is a class IA antiarrhythmic drug that acts as a sodium channel blocker by blocking fast sodium channels. Mexiletine is a class IB antiarrhythmic drug, not class IA. Amiodarone is a class III antiarrhythmic, and Quinidine is a class IA antiarrhythmic but not a sodium channel blocker.

5. A client has a new prescription for Tetracycline. Which of the following instructions should be included?

Correct answer: B

Rationale: The correct instruction to include for a client prescribed Tetracycline is to 'Avoid prolonged sun exposure.' Tetracycline can cause photosensitivity, making the client more sensitive to the sun's rays. This can lead to adverse reactions like sunburn or skin rashes. Therefore, it is crucial for the client to minimize sun exposure and wear protective clothing when outdoors. Choice A is incorrect because taking Tetracycline with milk can reduce its absorption. Choice C is incorrect as there is no specific requirement to take Tetracycline at bedtime. Choice D is also incorrect as Tetracycline does not typically cause dark yellow urine.

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