which of the following drugs is associated with the reaction of cinchonism

ATI RN

ATI Pharmacology Proctored

1. Which of the following drugs is associated with the reaction of Cinchonism?

A. Valproic acid
B. Quinidine
C. Isoniazid
D. Ethosuximide

Correct answer: B

Rationale: Cinchonism is associated with Quinidine, not Valproic acid, Isoniazid, or Ethosuximide. Cinchonism is characterized by symptoms such as tinnitus, dizziness, and headaches. Quinidine, being an antiarrhythmic agent, can lead to this condition as a side effect.

2. A client has a new prescription for Alendronate to treat osteoporosis. Which of the following instructions should the nurse include?

A. Take the medication with a full glass of water after rising in the morning.
B. Lie down for at least 30 minutes after taking the medication.
C. Take the medication before bedtime to reduce the risk of esophageal irritation.
D. Crush the tablet and mix it with applesauce if having difficulty swallowing.

Correct answer: A

Rationale: The correct instruction is to take Alendronate with a full glass of water after rising in the morning. This helps reduce the risk of esophageal irritation, as the medication can cause irritation if not taken correctly. Taking it before bedtime (choice C) can increase the risk of irritation as the individual lies down. Lying down after taking the medication (choice B) can also lead to esophageal irritation. Crushing the tablet (choice D) is not recommended as Alendronate should be taken whole with a full glass of water.

3. What is levothyroxine's pharmacologic classification?

A. Thyroid Preparations
B. Metabolic Inhibitors
C. Analgesic
D. Loop Diuretic

Correct answer: A

Rationale: Levothyroxine is classified as a thyroid preparation because it is a synthetic form of the thyroid hormone thyroxine. It is primarily used to treat hypothyroidism by supplementing or replacing the natural thyroid hormones in the body, helping to regulate metabolism and energy levels. Choice B, Metabolic Inhibitors, is incorrect because levothyroxine does not inhibit metabolism but rather helps regulate it. Choice C, Analgesic, is incorrect as levothyroxine is not used for pain relief but for thyroid hormone replacement therapy. Choice D, Loop Diuretic, is also incorrect as loop diuretics are medications that act on the kidneys to increase urine production and are not related to thyroid hormone replacement therapy.

4. A client has a new prescription for Lithium Carbonate. When teaching the client about ways to prevent Lithium toxicity, what advice should the nurse provide?

A. Avoid using acetaminophen for headaches.
B. Restrict intake of foods high in sodium.
C. Decrease fluid intake to less than 1,500 mL daily.
D. Limit aerobic activity in hot weather.

Correct answer: D

Rationale: The nurse should advise the client to limit aerobic activity in hot weather to prevent sodium/water depletion, which can increase the risk for Lithium toxicity. Excessive sweating and fluid loss can lead to dehydration and changes in lithium levels, potentially resulting in toxicity. Choices A, B, and C are incorrect. Avoiding acetaminophen for headaches is not directly related to Lithium toxicity. Restricting sodium intake and decreasing fluid intake can lead to increased lithium levels and toxicity, so these are not recommended actions.

5. What classification of drug is Penicillin?

A. Antiarrhythmic
B. Anticonvulsant
C. Antibacterial
D. Mood stabilizer

Correct answer: C

Rationale: Penicillin is classified as an antibacterial drug, specifically used to treat bacterial infections. It works by inhibiting the growth of bacteria, making it an effective treatment for various bacterial infections. Choices A, B, and D are incorrect as Penicillin does not belong to these drug classifications. Penicillin does not have any direct effect on heart rhythm (antiarrhythmic), does not treat seizures (anticonvulsant), and is not used to stabilize mood (mood stabilizer).