ATI RN
ATI Proctored Pharmacology 2023
1. What does it mean when a medication has a half-life?
- A. It only lasts for 30 minutes after the medication is given
- B. How long it takes for half of the dose to be eliminated from the bloodstream
- C. It is the peak of how effective the medicine is
- D. Drug is greatly reduced before it reaches the systemic circulation
Correct answer: B
Rationale: When a medication has a half-life, it refers to the time it takes for half of the dose to be eliminated from the bloodstream. This parameter is crucial in understanding the duration of action and dosing intervals for medications in clinical practice. Choice A is incorrect as the half-life is not about how long the medication lasts but about elimination from the body. Choice C is incorrect because the half-life is not about the peak effectiveness of the medicine. Choice D is incorrect as it does not accurately define the concept of half-life.
2. Which of the following is classified as a class IA Sodium Channel blocker?
- A. Quinidine
- B. Disopyramide
- C. Aminodarone
- D. Propafenone
Correct answer: A
Rationale: Quinidine is classified as a class IA sodium channel blocker. Class IA antiarrhythmics, like quinidine, work by blocking sodium channels and delaying repolarization. Propafenone, mentioned in the original rationale, is actually a class IC antiarrhythmic agent, not a class IA sodium channel blocker.
3. A client has a new prescription for Beclomethasone. Which of the following instructions should the nurse include?
- A. Rinse your mouth after each use of this medication.
- B. Limit fluid intake while taking this medication.
- C. Increase your intake of vitamin B12 while taking this medication.
- D. You can take the medication as needed.
Correct answer: A
Rationale: The correct instruction for a client prescribed Beclomethasone is to rinse the mouth after each use to reduce the risk of oral fungal infection. Beclomethasone is a corticosteroid inhaler that can increase the risk of oral thrush, so rinsing the mouth helps minimize this side effect. Choice B is incorrect because there is no need to limit fluid intake while taking Beclomethasone. Choice C is incorrect as there is no specific need to increase vitamin B12 intake with this medication. Choice D is incorrect because Beclomethasone should be taken as prescribed, not as needed.
4. A nurse is caring for a client who has a new prescription for Metformin. Which of the following instructions should the nurse include?
- A. Take this medication with food.
- B. Avoid eating foods high in potassium.
- C. Take this medication at bedtime.
- D. Take this medication every other day.
Correct answer: A
Rationale: The correct instruction for a client prescribed Metformin is to take the medication with food. Taking Metformin with meals helps reduce gastrointestinal side effects and ensures better absorption. Choice B, to avoid foods high in potassium, is not directly related to Metformin. Choice C, taking the medication at bedtime, is not a standard instruction for Metformin. Choice D, taking the medication every other day, is incorrect as Metformin is typically taken daily as prescribed.
5. A healthcare provider is completing a client's medical history. The client takes Simvastatin. The healthcare provider should identify which of the following disorders as a contraindication to adding Ezetimibe to the client's medications?
- A. History of severe constipation
- B. History of hypertension
- C. Active hepatitis C
- D. Type 2 diabetes mellitus
Correct answer: C
Rationale: Ezetimibe is contraindicated in patients with active moderate-to-severe liver disorders, such as active hepatitis C, especially when they are already taking a statin like simvastatin. This combination can increase the risk of liver problems and is not recommended due to the potential for further liver damage. Choices A, B, and D are not directly contraindications for adding Ezetimibe to the client's medications.
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